Synergistic effect of interaction between perceived health and social activity on depressive symptoms in the middle-aged and elderly

A population-based longitudinal study

Sung Youn Chun, Kyu Tae Han, Seo Yoon Lee, Chan Ok Kim, Euncheol Park

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective: To examine the synergistic effect of interaction between perceived health and social activity on depressive symptoms. Methods: We investigated whether the interaction between perceived health and social activity has a synergistic effect on depressive symptoms in the middle-aged and elderly using data from 6590 respondents aged 45 and older in the Korean Longitudinal Study on Aging (KLoSA), 2006-2012. A generalised linear mixed-effects model was used to investigate the association in a longitudinal data form. Depressive symptoms were measured using the Center for Epidemiological Studies Depression 10 Scale (CES-D10). Perceived health and level of social activity were categorical variables with three values. Participation in six social activities was assessed. Results: Interactions between perceived health status and social activity were statistically significant for almost all social activity/perceived health combinations. Addition of the interaction term significantly decreased CES-D10 scores, confirming the synergistic effect of the interaction between perceived health status and social activity ('normalxmoderate', β=-0.1826; 'poorxmoderate', β=-0.5739; 'poorxactive' , β=-0.8935). In addition, we performed stratified analyses by region: urban or rural. In urban respondents, the additional effect of the interaction term decreased CES-D10 scores and all social activity/perceived health combinations were statistically significant ('normalxmoderate', β=-0.2578; 'normalxactive', β=-0.3945; 'poorxmoderate', β=-0.5739; 'poorxactive' , β=-0.8935). In rural respondents, only one social activity/perceived health combination was statistically significant, and the additional effect of the interaction term showed no consistent trend on CES-D10 scores. Conclusions: The interaction between perceived health and social activity has a synergistic effect on depressive symptoms; the additional effect of the interaction term significantly decreased CES-D10 scores in our models.

Original languageEnglish
Article numbere007154
JournalBMJ Open
Volume5
Issue number3
DOIs
Publication statusPublished - 2015 Jan 1

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Longitudinal Studies
Depression
Health
Epidemiologic Studies
Population
Health Status
Surveys and Questionnaires

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{a1567a03c4984bcab6bd0d976dd65bcd,
title = "Synergistic effect of interaction between perceived health and social activity on depressive symptoms in the middle-aged and elderly: A population-based longitudinal study",
abstract = "Objective: To examine the synergistic effect of interaction between perceived health and social activity on depressive symptoms. Methods: We investigated whether the interaction between perceived health and social activity has a synergistic effect on depressive symptoms in the middle-aged and elderly using data from 6590 respondents aged 45 and older in the Korean Longitudinal Study on Aging (KLoSA), 2006-2012. A generalised linear mixed-effects model was used to investigate the association in a longitudinal data form. Depressive symptoms were measured using the Center for Epidemiological Studies Depression 10 Scale (CES-D10). Perceived health and level of social activity were categorical variables with three values. Participation in six social activities was assessed. Results: Interactions between perceived health status and social activity were statistically significant for almost all social activity/perceived health combinations. Addition of the interaction term significantly decreased CES-D10 scores, confirming the synergistic effect of the interaction between perceived health status and social activity ('normalxmoderate', β=-0.1826; 'poorxmoderate', β=-0.5739; 'poorxactive' , β=-0.8935). In addition, we performed stratified analyses by region: urban or rural. In urban respondents, the additional effect of the interaction term decreased CES-D10 scores and all social activity/perceived health combinations were statistically significant ('normalxmoderate', β=-0.2578; 'normalxactive', β=-0.3945; 'poorxmoderate', β=-0.5739; 'poorxactive' , β=-0.8935). In rural respondents, only one social activity/perceived health combination was statistically significant, and the additional effect of the interaction term showed no consistent trend on CES-D10 scores. Conclusions: The interaction between perceived health and social activity has a synergistic effect on depressive symptoms; the additional effect of the interaction term significantly decreased CES-D10 scores in our models.",
author = "Chun, {Sung Youn} and Han, {Kyu Tae} and Lee, {Seo Yoon} and Kim, {Chan Ok} and Euncheol Park",
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Synergistic effect of interaction between perceived health and social activity on depressive symptoms in the middle-aged and elderly : A population-based longitudinal study. / Chun, Sung Youn; Han, Kyu Tae; Lee, Seo Yoon; Kim, Chan Ok; Park, Euncheol.

In: BMJ Open, Vol. 5, No. 3, e007154, 01.01.2015.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Synergistic effect of interaction between perceived health and social activity on depressive symptoms in the middle-aged and elderly

T2 - A population-based longitudinal study

AU - Chun, Sung Youn

AU - Han, Kyu Tae

AU - Lee, Seo Yoon

AU - Kim, Chan Ok

AU - Park, Euncheol

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Objective: To examine the synergistic effect of interaction between perceived health and social activity on depressive symptoms. Methods: We investigated whether the interaction between perceived health and social activity has a synergistic effect on depressive symptoms in the middle-aged and elderly using data from 6590 respondents aged 45 and older in the Korean Longitudinal Study on Aging (KLoSA), 2006-2012. A generalised linear mixed-effects model was used to investigate the association in a longitudinal data form. Depressive symptoms were measured using the Center for Epidemiological Studies Depression 10 Scale (CES-D10). Perceived health and level of social activity were categorical variables with three values. Participation in six social activities was assessed. Results: Interactions between perceived health status and social activity were statistically significant for almost all social activity/perceived health combinations. Addition of the interaction term significantly decreased CES-D10 scores, confirming the synergistic effect of the interaction between perceived health status and social activity ('normalxmoderate', β=-0.1826; 'poorxmoderate', β=-0.5739; 'poorxactive' , β=-0.8935). In addition, we performed stratified analyses by region: urban or rural. In urban respondents, the additional effect of the interaction term decreased CES-D10 scores and all social activity/perceived health combinations were statistically significant ('normalxmoderate', β=-0.2578; 'normalxactive', β=-0.3945; 'poorxmoderate', β=-0.5739; 'poorxactive' , β=-0.8935). In rural respondents, only one social activity/perceived health combination was statistically significant, and the additional effect of the interaction term showed no consistent trend on CES-D10 scores. Conclusions: The interaction between perceived health and social activity has a synergistic effect on depressive symptoms; the additional effect of the interaction term significantly decreased CES-D10 scores in our models.

AB - Objective: To examine the synergistic effect of interaction between perceived health and social activity on depressive symptoms. Methods: We investigated whether the interaction between perceived health and social activity has a synergistic effect on depressive symptoms in the middle-aged and elderly using data from 6590 respondents aged 45 and older in the Korean Longitudinal Study on Aging (KLoSA), 2006-2012. A generalised linear mixed-effects model was used to investigate the association in a longitudinal data form. Depressive symptoms were measured using the Center for Epidemiological Studies Depression 10 Scale (CES-D10). Perceived health and level of social activity were categorical variables with three values. Participation in six social activities was assessed. Results: Interactions between perceived health status and social activity were statistically significant for almost all social activity/perceived health combinations. Addition of the interaction term significantly decreased CES-D10 scores, confirming the synergistic effect of the interaction between perceived health status and social activity ('normalxmoderate', β=-0.1826; 'poorxmoderate', β=-0.5739; 'poorxactive' , β=-0.8935). In addition, we performed stratified analyses by region: urban or rural. In urban respondents, the additional effect of the interaction term decreased CES-D10 scores and all social activity/perceived health combinations were statistically significant ('normalxmoderate', β=-0.2578; 'normalxactive', β=-0.3945; 'poorxmoderate', β=-0.5739; 'poorxactive' , β=-0.8935). In rural respondents, only one social activity/perceived health combination was statistically significant, and the additional effect of the interaction term showed no consistent trend on CES-D10 scores. Conclusions: The interaction between perceived health and social activity has a synergistic effect on depressive symptoms; the additional effect of the interaction term significantly decreased CES-D10 scores in our models.

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