Syntheses of phosphorylcholine-substituted silsesquioxanes via thiol-ene 'click' reaction

Lei Liu, Su Jung Lee, Myong Euy Lee, Philjae Kang, Moon Gun Choi

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Phosphorylcholine-substituted silsesquioxanes were synthesized via the UV-initiated thiol-ene 'click' reaction of octakis(3-mercaptopropyl)octasilsesquioxane (POSS-SH) with 2-methacryloyloxyethylphosphorylcholine or allylphosphorylcholine in mixed (DMF/MeOH) solvents, respectively. In addition, the crystal structures of POSS-SH and MPC were first determined.

Original languageEnglish
Pages (from-to)1562-1565
Number of pages4
JournalTetrahedron Letters
Issue number12
Publication statusPublished - 2015 Mar 18

Bibliographical note

Funding Information:
This research was supported by the Research and Education Center for Advanced Silicon Materials (RECASM) financially supported by the KCC Corporation . The authors also thank the KCI for providing chemicals.

Publisher Copyright:
© 2015 Elsevier Ltd. All rights reserved.

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


Dive into the research topics of 'Syntheses of phosphorylcholine-substituted silsesquioxanes via thiol-ene 'click' reaction'. Together they form a unique fingerprint.

Cite this