Synthesis and antibacterial activity of novel 2-oxo-pyrrolidinyl oxazolidinones

Deepak Bhattarai, Sun Hee Lee, Hyeong Kyu Kim, Soon Bang Kang, Ae Nim Pae, Eunice Eunkyeong Kim, Taegwon Oh, Sang Nae Cho, Gyochang Keum

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Abstract

Novel antibacterial oxazolidinones bearing pyrrolidinone ring system at the C-5 side chain were synthesized and their in vitro antibacterial activities were evaluated. Most of the synthesized oxazolidinones showed good antibacterial activity against the Gram-positive and Gram-negative bacteria tested.

Original languageEnglish
Pages (from-to)1310-1316
Number of pages7
JournalBulletin of the Korean Chemical Society
Volume33
Issue number4
DOIs
Publication statusPublished - 2012 Apr 20

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All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

Bhattarai, D., Lee, S. H., Kim, H. K., Kang, S. B., Pae, A. N., Kim, E. E., Oh, T., Cho, S. N., & Keum, G. (2012). Synthesis and antibacterial activity of novel 2-oxo-pyrrolidinyl oxazolidinones. Bulletin of the Korean Chemical Society, 33(4), 1310-1316. https://doi.org/10.5012/bkcs.2012.33.4.1310