Synthesis and anticancer activity of novel deoxoartemisinin-glycolipid hybrids

Dongguk Min, Minkyu Kim, Jéŕemy Ricci, Sora Jung, Kirim Kim, Won Yoon Chung, Kwang Kyun Park, Mankil Jung

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The practical synthesis and anticancer activity of novel deoxoartemisinin-glycolipid hybrids, which incorporate two drugs into a single molecule and can impact multiple targets simultaneously are presented. These hybrids exhibited potent in vitro anticancer activity against several human cancer cell lines. The deoxoartemisinin- glycolipid hybrids generally demonstrated better anticancer activity than either artemisinin or daumone alone and cisplatin.

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

Cite this