The practical synthesis and anticancer activity of novel deoxoartemisinin-glycolipid hybrids, which incorporate two drugs into a single molecule and can impact multiple targets simultaneously are presented. These hybrids exhibited potent in vitro anticancer activity against several human cancer cell lines. The deoxoartemisinin- glycolipid hybrids generally demonstrated better anticancer activity than either artemisinin or daumone alone and cisplatin.
All Science Journal Classification (ASJC) codes
- Drug Discovery