Synthesis and Characterization of a New Class of Triazoles Containing Bicyclic Silaheterocycles

Tengjiao Wang, Hyeon Mo Cho, Myong Euy Lee

Research output: Contribution to journalArticle

Abstract

A new class of bicyclic silaheterocycles, 6,6-dimethyl-2-aryl-6,7-dihydro-5H-[1,2,4]triazolo[5,1-b][1,3,5]thiazasilines, which could be developed as potential sila-drugs. The reactions of several 3-aryl-5-mercapto-1,2,4-triazoles with bis(chloromethyl)dimethylsilane under basic conditions gave high yields of bicyclic products. Reaction, product workup and isolation were streamlined without requiring an anhydrous solvent, inert gas or chromatographic purification. The products were structurally characterized by single-crystal X-ray diffraction.

Original languageEnglish
Pages (from-to)3673-3675
Number of pages3
JournalChemistrySelect
Volume2
Issue number13
DOIs
Publication statusPublished - 2017 Jan 1

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Noble Gases
Triazoles
Reaction products
Purification
Single crystals
X ray diffraction
Pharmaceutical Preparations
1,2,4-triazole

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

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Synthesis and Characterization of a New Class of Triazoles Containing Bicyclic Silaheterocycles. / Wang, Tengjiao; Cho, Hyeon Mo; Lee, Myong Euy.

In: ChemistrySelect, Vol. 2, No. 13, 01.01.2017, p. 3673-3675.

Research output: Contribution to journalArticle

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