Synthesis and Cytotoxicity of Dendritic Platinum Nanoparticles with HEK-293 Cells

Kyubin Shim, Jeonghun Kim, Yoon Uk Heo, Bo Jiang, Cuiling Li, Mohammed Shahabuddin, Kevin C.W. Wu, Md Shahriar A. Hossain, Yusuke Yamauchi, Jung Ho Kim

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Dendritic platinum nanoparticles (DPNs) have been synthesized from l-ascorbic acid and an amphiphilic non-ionic surfactant (Brij-58) via a sonochemical method. The particle size and shape of the DPNs could be tuned by changing the reduction temperature, resulting in a uniform DPN with a size of 23 nm or 60 nm. The facets of DPNs have been studied by high-resolution transmission electron microscopy. The cytotoxicity of DPNs has been investigated using human embryonic kidney cells (HEK-293), and the biological adaptability exhibited by DPNs has opened a pathway to biomedical applications such as drug-delivery systems, photothermal treatment, and biosensors.

Original languageEnglish
Pages (from-to)21-26
Number of pages6
JournalChemistry - An Asian Journal
Volume12
Issue number1
DOIs
Publication statusPublished - 2017 Jan 3

Bibliographical note

Publisher Copyright:
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Synthesis and Cytotoxicity of Dendritic Platinum Nanoparticles with HEK-293 Cells'. Together they form a unique fingerprint.

Cite this