TY - JOUR
T1 - Synthesis and Cytotoxicity of Dendritic Platinum Nanoparticles with HEK-293 Cells
AU - Shim, Kyubin
AU - Kim, Jeonghun
AU - Heo, Yoon Uk
AU - Jiang, Bo
AU - Li, Cuiling
AU - Shahabuddin, Mohammed
AU - Wu, Kevin C.W.
AU - Hossain, Md Shahriar A.
AU - Yamauchi, Yusuke
AU - Kim, Jung Ho
N1 - Publisher Copyright:
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2017/1/3
Y1 - 2017/1/3
N2 - Dendritic platinum nanoparticles (DPNs) have been synthesized from l-ascorbic acid and an amphiphilic non-ionic surfactant (Brij-58) via a sonochemical method. The particle size and shape of the DPNs could be tuned by changing the reduction temperature, resulting in a uniform DPN with a size of 23 nm or 60 nm. The facets of DPNs have been studied by high-resolution transmission electron microscopy. The cytotoxicity of DPNs has been investigated using human embryonic kidney cells (HEK-293), and the biological adaptability exhibited by DPNs has opened a pathway to biomedical applications such as drug-delivery systems, photothermal treatment, and biosensors.
AB - Dendritic platinum nanoparticles (DPNs) have been synthesized from l-ascorbic acid and an amphiphilic non-ionic surfactant (Brij-58) via a sonochemical method. The particle size and shape of the DPNs could be tuned by changing the reduction temperature, resulting in a uniform DPN with a size of 23 nm or 60 nm. The facets of DPNs have been studied by high-resolution transmission electron microscopy. The cytotoxicity of DPNs has been investigated using human embryonic kidney cells (HEK-293), and the biological adaptability exhibited by DPNs has opened a pathway to biomedical applications such as drug-delivery systems, photothermal treatment, and biosensors.
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U2 - 10.1002/asia.201601239
DO - 10.1002/asia.201601239
M3 - Article
C2 - 27911052
AN - SCOPUS:85006136222
VL - 12
SP - 21
EP - 26
JO - Chemistry - An Asian Journal
JF - Chemistry - An Asian Journal
SN - 1861-4728
IS - 1
ER -