Synthesis of 2,3-disubstituted indole on solid phase by the fischer indole synthesis

Han Seo Mun, Won Hun Ham, Jin Hyun Jeong

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

2,3-Disubstituted indoles were synthesized by solid-phase reaction using the Fischer indole synthesis. A "traceless" silicon linker was employed with the silicon - carbon bonding being cleaved with TFA. An oxygen atom was placed into the middle of the spacer/linker so as to enhance solid-phase synthesis by better solvation.

Original languageEnglish
Pages (from-to)130-135
Number of pages6
JournalJournal of Combinatorial Chemistry
Volume7
Issue number1
DOIs
Publication statusPublished - 2005 Jan 1

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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