Synthesis of 5-aminolevulinic acid (ALA) and its t-Butyl ester for the fluorescence detection of early cancer

Min Seok Kang; Dong Myung Kim; Sook Kim Jeong; Jin Hyun Jeong

doi:10.1007/BF02972970

Synthesis of 5-aminolevulinic acid (ALA) and its t-Butyl ester for the fluorescence detection of early cancer

Min Seok Kang, Dong Myung Kim, Sook Kim Jeong, Jin Hyun Jeong

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

5-Aminolevulinic acid and its derivatives, which are known to affect the early diagnosis and treatment of cancer, have been synthesized. Simple methods for the synthesis of 5-aminolevulinic acid (ALA), a precursor of porphyrins, have been developed in our laboratory for use in studies on the biosynthesis of porphyrins.

Original language	English
Pages (from-to)	1111-1113
Number of pages	3
Journal	Archives of pharmacal research
Volume	28
Issue number	10
DOIs	https://doi.org/10.1007/BF02972970
Publication status	Published - 2005 Oct 31

Bibliographical note

Funding Information:
This research was supported by the Kyung Hee University, 2005 Research Funding and and Korea Institute of Industial Technology Evaluation and Planning (M 1-0310-22-0002).

All Science Journal Classification (ASJC) codes

Molecular Medicine
Drug Discovery
Organic Chemistry

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title = "Synthesis of 5-aminolevulinic acid (ALA) and its t-Butyl ester for the fluorescence detection of early cancer",

abstract = "5-Aminolevulinic acid and its derivatives, which are known to affect the early diagnosis and treatment of cancer, have been synthesized. Simple methods for the synthesis of 5-aminolevulinic acid (ALA), a precursor of porphyrins, have been developed in our laboratory for use in studies on the biosynthesis of porphyrins.",

author = "Kang, {Min Seok} and Kim, {Dong Myung} and Jeong, {Sook Kim} and Jeong, {Jin Hyun}",

note = "Funding Information: This research was supported by the Kyung Hee University, 2005 Research Funding and and Korea Institute of Industial Technology Evaluation and Planning (M 1-0310-22-0002).",

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AU - Kang, Min Seok

AU - Kim, Dong Myung

AU - Jeong, Sook Kim

AU - Jeong, Jin Hyun

N1 - Funding Information: This research was supported by the Kyung Hee University, 2005 Research Funding and and Korea Institute of Industial Technology Evaluation and Planning (M 1-0310-22-0002).

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Y1 - 2005/10/31

N2 - 5-Aminolevulinic acid and its derivatives, which are known to affect the early diagnosis and treatment of cancer, have been synthesized. Simple methods for the synthesis of 5-aminolevulinic acid (ALA), a precursor of porphyrins, have been developed in our laboratory for use in studies on the biosynthesis of porphyrins.

AB - 5-Aminolevulinic acid and its derivatives, which are known to affect the early diagnosis and treatment of cancer, have been synthesized. Simple methods for the synthesis of 5-aminolevulinic acid (ALA), a precursor of porphyrins, have been developed in our laboratory for use in studies on the biosynthesis of porphyrins.

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