Synthesis of curcumin/polyrhodanine nanocapsules with antimicrobial properties by oxidative polymerization using the Fenton reaction

Jun Won Kook, Soyeon Kim, Jun Young Lee, Jung Hyun Kim

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Curcumin exhibits various biological activities; however, its applications are limited because of its poor water solubility. In this study, we describe an encapsulation process that improves this property using a polyrhodanine shell material synthesized by oxidative polymerization. Unlike the previous methods of oxidative polymerizations, we used the Fenton reaction to introduce a FeCl3/H2O2 combination system. By changing the rhodanine monomer ratio, the curcumin/polyrhodanine nanocapsule (CPR-NC) shell thickness could be controlled. The release behavior of curcumin was characterized by UV–Vis spectroscopy over time. Antimicrobial tests with curcumin, polyrhodanine, and CPR-NC were performed to analyze the minimum inhibitory concentration and inhibition zones.

Original languageEnglish
Pages (from-to)125-130
Number of pages6
JournalReactive and Functional Polymers
Volume109
DOIs
Publication statusPublished - 2016 Dec 1

Bibliographical note

Funding Information:
This work was supported by the Ministry of Trade Industry and Energy/Korea Evaluation Institute of Industrial Technology ( KEIT ) ( 10050039 ), and the Nano-Material Technology Development Program through the National Research Foundation of Korea ( NRF ) funded by the Ministry of Science, ICT & Future Planning (MSIP, Korea) (NRF- 2014M3A7B4050960 / 2014M3A7B4051745 ). The first two authors Jun.-Won Kook and Soyeon Kim contributed equally to this work.

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Environmental Chemistry
  • Biochemistry
  • Chemical Engineering(all)
  • Polymers and Plastics
  • Materials Chemistry

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