Curcumin exhibits various biological activities; however, its applications are limited because of its poor water solubility. In this study, we describe an encapsulation process that improves this property using a polyrhodanine shell material synthesized by oxidative polymerization. Unlike the previous methods of oxidative polymerizations, we used the Fenton reaction to introduce a FeCl3/H2O2 combination system. By changing the rhodanine monomer ratio, the curcumin/polyrhodanine nanocapsule (CPR-NC) shell thickness could be controlled. The release behavior of curcumin was characterized by UV–Vis spectroscopy over time. Antimicrobial tests with curcumin, polyrhodanine, and CPR-NC were performed to analyze the minimum inhibitory concentration and inhibition zones.
|Number of pages||6|
|Journal||Reactive and Functional Polymers|
|Publication status||Published - 2016 Dec 1|
Bibliographical noteFunding Information:
This work was supported by the Ministry of Trade Industry and Energy/Korea Evaluation Institute of Industrial Technology ( KEIT ) ( 10050039 ), and the Nano-Material Technology Development Program through the National Research Foundation of Korea ( NRF ) funded by the Ministry of Science, ICT & Future Planning (MSIP, Korea) (NRF- 2014M3A7B4050960 / 2014M3A7B4051745 ). The first two authors Jun.-Won Kook and Soyeon Kim contributed equally to this work.
© 2016 Elsevier B.V.
All Science Journal Classification (ASJC) codes
- Environmental Chemistry
- Chemical Engineering(all)
- Polymers and Plastics
- Materials Chemistry