Synthesis of nano-cuboidal gold particles for effective antimicrobial property against clinical human pathogens

Paskalis Sahaya Murphin Kumar, Davoodbasha MubarakAli, Rijuta Ganesh Saratale, Ganesh Dattatraya Saratale, Arivalagan Pugazhendhi, Kumar Gopalakrishnan, Nooruddin Thajuddin

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Algae could offer a potential source of fine chemicals, pharmaceuticals and biofuels. In this study, a green synthesis of dispersed cuboidal gold nanoparticles (AuNPs) was achieved using red algae, Gelidium amansii reacted with HAuCl4. It was found to be 4–7 nm sized cubical nanoparticles with aspect ratio of 1.4 were synthesized using 0.5 mM of HAuCl4 by HRSEM analysis. The crystalline planes (111), (200), (220), (311) and elemental signal of gold was observed by XRD and EDS respectively. The major constitutes, galactose and 3,6-anhydrogalactose in the alga played a critical role in the synthesis of crystalline AuNPs with cubical dimension. Further, the antibacterial potential of synthesized AuNPs was tested against human pathogens, Escherichia coli and Staphylococcus aureus. The synthesized AuNPs found biocompatible up to 100 ppm and high concentration showed an inhibition against cancer cell. This novel report could be helped to exploration of bioresources to material synthesis for the application of biosensor and biomedical application.

Original languageEnglish
Pages (from-to)68-73
Number of pages6
JournalMicrobial Pathogenesis
Volume113
DOIs
Publication statusPublished - 2017 Dec

Fingerprint

Gold
Nanoparticles
Rhodophyta
Biofuels
Biosensing Techniques
Galactose
Staphylococcus aureus
Escherichia coli
Pharmaceutical Preparations
Neoplasms
acid gold tetrachloride
3,6-anhydrogalactose

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Infectious Diseases

Cite this

Murphin Kumar, Paskalis Sahaya ; MubarakAli, Davoodbasha ; Saratale, Rijuta Ganesh ; Saratale, Ganesh Dattatraya ; Pugazhendhi, Arivalagan ; Gopalakrishnan, Kumar ; Thajuddin, Nooruddin. / Synthesis of nano-cuboidal gold particles for effective antimicrobial property against clinical human pathogens. In: Microbial Pathogenesis. 2017 ; Vol. 113. pp. 68-73.
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Synthesis of nano-cuboidal gold particles for effective antimicrobial property against clinical human pathogens. / Murphin Kumar, Paskalis Sahaya; MubarakAli, Davoodbasha; Saratale, Rijuta Ganesh; Saratale, Ganesh Dattatraya; Pugazhendhi, Arivalagan; Gopalakrishnan, Kumar; Thajuddin, Nooruddin.

In: Microbial Pathogenesis, Vol. 113, 12.2017, p. 68-73.

Research output: Contribution to journalArticle

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