Synthesis of new C2-symmetric bioxazoles and application as chiral ligands in asymmetric hydrosilylation

Sang Gi Lee, Chung Woo Lim, Choong Eui Song, In O. Kim, Chul Ho Jun

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)

Abstract

New C2-symmetric chiral (4S,4'S)-bioxazoles 3a and 3b, possessing chirality on their backbone, were synthesized efficiently starting from L-tartaric acid. The structure of 3a was determined by X-ray crystal structure analysis. With these novel chiral bioxazole ligands, as a preliminary investigation for their effects on the enantioselectivity, rhodium(I)-catalyzed enantioselective hydrosilylations of acetophenone were carried out.

Original languageEnglish
Pages (from-to)2927-2932
Number of pages6
JournalTetrahedron Asymmetry
Volume8
Issue number17
DOIs
Publication statusPublished - 1997 Sep 11

Bibliographical note

Funding Information:
This research was supported by grant from Ministry of Science and Technology like to thank Dr K. M. Kim for help with X-ray analysis.

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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