New C2-symmetric chiral (4S,4'S)-bioxazoles 3a and 3b, possessing chirality on their backbone, were synthesized efficiently starting from L-tartaric acid. The structure of 3a was determined by X-ray crystal structure analysis. With these novel chiral bioxazole ligands, as a preliminary investigation for their effects on the enantioselectivity, rhodium(I)-catalyzed enantioselective hydrosilylations of acetophenone were carried out.
Bibliographical noteFunding Information:
This research was supported by grant from Ministry of Science and Technology like to thank Dr K. M. Kim for help with X-ray analysis.
All Science Journal Classification (ASJC) codes
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry