Many diselenide compounds are used as antioxidants, enzyme inhibitors and cytokine inducers. Three new diselenide compounds, bis-(2-hydroxyphenyl) diselenide, bis-(3-hydroxyphenyl) diselenide and bis-(4-hydroxyphenyl) diselenide were designed and synthesized as antiinflammatory agent. All of them were found to have strong in vitro activity in anti-inflammatory assays.
Bibliographical noteFunding Information:
This research was funded by grant No. M1-0310-22-0002 from the program of the Korean Science & Engineering Foundation.
All Science Journal Classification (ASJC) codes
- Molecular Medicine
- Drug Discovery
- Organic Chemistry