Abstract
New glycosylated peptidomimetics possessing O- and N-glycosylated α-aminooxy acids were efficiently synthesized by fragment coupling on solid support. The N-terminal glycosylated tripeptide mimics prepared in solution were coupled to the C-terminal dipeptides attached to the resin under O-(7-azabenzotriazole-I-yl)-1, 1, 3, 3-tetramethyluronium hexafluorophosphate (HATU)/1-hydroxy-7-azabenzotriazole (HOAt)/N-ethylmorpholin (NEM) conditions.
| Original language | English |
|---|---|
| Pages (from-to) | 1463-1466 |
| Number of pages | 4 |
| Journal | Synlett |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 2002 Jan 1 |
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All Science Journal Classification (ASJC) codes
- Organic Chemistry
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Synthesis of novel glycopeptidomimetics containing O- and N-glycosylated α-aminooxy acids by fragment coupling on solid support. / Lee, Myung Ryul; Lee, Jiyong; Shin, Injae.
In: Synlett, No. 9, 01.01.2002, p. 1463-1466.Research output: Contribution to journal › Article
TY - JOUR
T1 - Synthesis of novel glycopeptidomimetics containing O- and N-glycosylated α-aminooxy acids by fragment coupling on solid support
AU - Lee, Myung Ryul
AU - Lee, Jiyong
AU - Shin, Injae
PY - 2002/1/1
Y1 - 2002/1/1
N2 - New glycosylated peptidomimetics possessing O- and N-glycosylated α-aminooxy acids were efficiently synthesized by fragment coupling on solid support. The N-terminal glycosylated tripeptide mimics prepared in solution were coupled to the C-terminal dipeptides attached to the resin under O-(7-azabenzotriazole-I-yl)-1, 1, 3, 3-tetramethyluronium hexafluorophosphate (HATU)/1-hydroxy-7-azabenzotriazole (HOAt)/N-ethylmorpholin (NEM) conditions.
AB - New glycosylated peptidomimetics possessing O- and N-glycosylated α-aminooxy acids were efficiently synthesized by fragment coupling on solid support. The N-terminal glycosylated tripeptide mimics prepared in solution were coupled to the C-terminal dipeptides attached to the resin under O-(7-azabenzotriazole-I-yl)-1, 1, 3, 3-tetramethyluronium hexafluorophosphate (HATU)/1-hydroxy-7-azabenzotriazole (HOAt)/N-ethylmorpholin (NEM) conditions.
UR - http://www.scopus.com/inward/record.url?scp=0036373849&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036373849&partnerID=8YFLogxK
U2 - 10.1055/s-2002-33509
DO - 10.1055/s-2002-33509
M3 - Article
AN - SCOPUS:0036373849
SP - 1463
EP - 1466
JO - Synlett
JF - Synlett
SN - 0936-5214
IS - 9
ER -