Synthesis of novel glycopeptidomimetics containing O- and N-glycosylated α-aminooxy acids by fragment coupling on solid support

Myung Ryul Lee, Jiyong Lee, Injae Shin

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12 Citations (Scopus)

Abstract

New glycosylated peptidomimetics possessing O- and N-glycosylated α-aminooxy acids were efficiently synthesized by fragment coupling on solid support. The N-terminal glycosylated tripeptide mimics prepared in solution were coupled to the C-terminal dipeptides attached to the resin under O-(7-azabenzotriazole-I-yl)-1, 1, 3, 3-tetramethyluronium hexafluorophosphate (HATU)/1-hydroxy-7-azabenzotriazole (HOAt)/N-ethylmorpholin (NEM) conditions.

Original languageEnglish
Pages (from-to)1463-1466
Number of pages4
JournalSynlett
Issue number9
DOIs
Publication statusPublished - 2002 Jan 1

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All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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