Synthesis of Pyrroles through Rhodium(III)-Catalyzed Reactions of Allylamines and Alkenes

Dong Su Kim, Yong Sik Seo, Chul Ho Jun

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Pyrrole derivatives are generated in reactions of allylamines with alkenes that are promoted by a Rh(III) catalyst in the presence of AgOAc. This process, which involves chelation assisted C-H bond activation and N-annulation, is applied to a three step synthesis of Zomepirac.

Original languageEnglish
Pages (from-to)3842-3845
Number of pages4
JournalOrganic Letters
Volume17
Issue number15
DOIs
Publication statusPublished - 2015 Aug 7

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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