Synthesis of Pyrroles through Rhodium(III)-Catalyzed Reactions of Allylamines and Alkenes

Dong Su Kim, Yong Sik Seo, Chul-Ho Jun

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Pyrrole derivatives are generated in reactions of allylamines with alkenes that are promoted by a Rh(III) catalyst in the presence of AgOAc. This process, which involves chelation assisted C-H bond activation and N-annulation, is applied to a three step synthesis of Zomepirac.

Original languageEnglish
Pages (from-to)3842-3845
Number of pages4
JournalOrganic Letters
Volume17
Issue number15
DOIs
Publication statusPublished - 2015 Aug 7

Fingerprint

Allylamine
Rhodium
chelation
Pyrroles
Alkenes
pyrroles
Chelation
rhodium
alkenes
Chemical activation
activation
Derivatives
catalysts
Catalysts
synthesis
zomepirac

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

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abstract = "Pyrrole derivatives are generated in reactions of allylamines with alkenes that are promoted by a Rh(III) catalyst in the presence of AgOAc. This process, which involves chelation assisted C-H bond activation and N-annulation, is applied to a three step synthesis of Zomepirac.",
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Synthesis of Pyrroles through Rhodium(III)-Catalyzed Reactions of Allylamines and Alkenes. / Kim, Dong Su; Seo, Yong Sik; Jun, Chul-Ho.

In: Organic Letters, Vol. 17, No. 15, 07.08.2015, p. 3842-3845.

Research output: Contribution to journalArticle

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