Synthesis of titanium oxide thin films containing antibacterial silver nanoparticles by a reactive magnetron co-sputtering system for application in biomedical implants

Doo Hoon Song, Soo Hyuk Uhm, Si Eun Kim, Jae Sung Kwon, Jeon Geon Han, Kyoung Nam Kim

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

Titanium oxide thin films containing silver (Ag) nanoparticles were synthesized on commercially pure titanium (cp-Ti) substrates using a reactive magnetron co-sputtering method. The goal was to maximize bactericidal activity along with sustained biocompatibility. Furthermore, this study examined the correlation between Ag nanoparticle dispersion in the films and the antibacterial efficacy of the Ag ions released from the films. The results showed that there might be two factors affecting the inhibition of bacterial attachment to the surface of the specimens: surface morphology and Ag ion release. MTT assay results demonstrated that there was no cytotoxicity on fibroblast cells in any group. Overall, the magnetron sputtered Ag nanoparticle-containing titanium oxide coatings in this study can be used as an efficient antibacterial layer with sustained biocompatibility.

Original languageEnglish
Pages (from-to)2994-2998
Number of pages5
JournalMaterials Research Bulletin
Volume47
Issue number10
DOIs
Publication statusPublished - 2012 Oct

Bibliographical note

Funding Information:
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology ( R13-2003-013-03001-0 ).

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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