Vitamin K3 (VK3) or 2-methyl-1,4-napthoquinone or menadione has been synthesized by selective oxidation of 2-methyl naphthalene (2-MN) with H2O2 using Zr-MCM-41(HT, hydrothermal) and Zr-MCM-41(TIE, template ion-exchange) catalysts. Different parameters affecting the oxidation of 2-MN like different Si/Zr ratios of catalysts, amount of the catalyst, reaction temperature, reaction time, 2-MN to H2O 2 molar ratio, concentration of acetonitrile and catalyst regenerability are described. In the catalytic reaction, the yield and selectivity of vitamin K3 in Zr-MCM-41(27)-TIE are higher than that of Zr-MCM-41(27)-HT due to increasing the catalytic activity within pores on the silica surface by completely template-ion exchanging through Zr-ions under TIE method. Thus a Zr-MCM-41(27)-TIE catalyst is the superior catalyst for the synthesis of VK3.
Bibliographical noteFunding Information:
The authors gratefully acknowledge the Korea Research Foundation for sponsoring this work (KRF-2003-005-D00002).
All Science Journal Classification (ASJC) codes
- Condensed Matter Physics
- Physical and Theoretical Chemistry
- Surfaces, Coatings and Films
- Materials Chemistry