Syringoma: A clinicopathologic and immunohistologic study and results of treatment

Ju Hee Lee, Jae Yong Chang, Kwang Hoon Lee

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29 Citations (Scopus)


The purpose of our study was to describe clinical and histopathological features of sixty one patients with histological diagnosis of syringoma over four year period in our dermatology clinic in Korea. Female:male ratio was 6.6:1 with onset of age cluting 2nd and 3rd decades in more than half of the patients in our study. The most frequently involved site was eyelids (43 cases, 70.5%) and the most common color of lesion was skin-color (30 cases, 49.2%). In 34 cases, characteristic lad-pole appearances (55.7%) were observed. Basal hyperpigmentation was observed more frequently in brown-colored lesion (p = 0.005). Fibrosis was observed more frequently in erythematous lesion (p = 0.033). Keratin cyst was observed less frequently in genital involved group (p = 0.006). We also performed immunohistochemical stain for the presence of progesterone receptor (PR) and estrogen receptor (ER) in fifty six cases with negative results.

Original languageEnglish
Pages (from-to)35-40
Number of pages6
JournalYonsei medical journal
Issue number1
Publication statusPublished - 2007 Feb

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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