t(5;12)(q13;p13) in acute myeloid leukemia with preceding granulocytic sarcoma

Tae Sung Park; Jaewoo Song; Kyung A. Lee; Sang Guk Lee; Yoo Hong Min; Jong Rak Choi

doi:10.1016/j.cancergencyto.2007.07.003

t(5;12)(q13;p13) in acute myeloid leukemia with preceding granulocytic sarcoma

Tae Sung Park, Jaewoo Song, Kyung A. Lee, Sang Guk Lee, Yoo Hong Min, Jong Rak Choi

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

A 56-year-old woman was brought to the emergency room with gum swelling and pain. Biopsy of the gingiva revealed sheet-like proliferation of myeloperoxidase and CD45-positive large cells, and she was diagnosed with granulocytic sarcoma. Two years later, bone marrow involvement of granulocytic sarcoma was suspected. Her chromosome study repeatedly revealed a 46,XX,t(5;12)(q13;p13) karyotype. Case reports of t(5;12)(q13;p13) are extremely rare in the literature. To our knowledge, this is the first report of t(5;12)(q13;p13) in a patient with acute myelogenous leukemia with preceding granulocytic sarcoma.

Original language	English
Pages (from-to)	158-160
Number of pages	3
Journal	Cancer genetics and cytogenetics
Volume	177
Issue number	2
DOIs	https://doi.org/10.1016/j.cancergencyto.2007.07.003
Publication status	Published - 2007 Sep

All Science Journal Classification (ASJC) codes

Molecular Biology
Genetics
Cancer Research

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10.1016/j.cancergencyto.2007.07.003

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@article{492c82e799d8475eb42dd40ebfc4bf73,

title = "t(5;12)(q13;p13) in acute myeloid leukemia with preceding granulocytic sarcoma",

abstract = "A 56-year-old woman was brought to the emergency room with gum swelling and pain. Biopsy of the gingiva revealed sheet-like proliferation of myeloperoxidase and CD45-positive large cells, and she was diagnosed with granulocytic sarcoma. Two years later, bone marrow involvement of granulocytic sarcoma was suspected. Her chromosome study repeatedly revealed a 46,XX,t(5;12)(q13;p13) karyotype. Case reports of t(5;12)(q13;p13) are extremely rare in the literature. To our knowledge, this is the first report of t(5;12)(q13;p13) in a patient with acute myelogenous leukemia with preceding granulocytic sarcoma.",

author = "Park, {Tae Sung} and Jaewoo Song and Lee, {Kyung A.} and Lee, {Sang Guk} and Min, {Yoo Hong} and Choi, {Jong Rak}",

year = "2007",

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doi = "10.1016/j.cancergencyto.2007.07.003",

language = "English",

volume = "177",

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T1 - t(5;12)(q13;p13) in acute myeloid leukemia with preceding granulocytic sarcoma

AU - Park, Tae Sung

AU - Song, Jaewoo

AU - Lee, Kyung A.

AU - Lee, Sang Guk

AU - Min, Yoo Hong

AU - Choi, Jong Rak

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N2 - A 56-year-old woman was brought to the emergency room with gum swelling and pain. Biopsy of the gingiva revealed sheet-like proliferation of myeloperoxidase and CD45-positive large cells, and she was diagnosed with granulocytic sarcoma. Two years later, bone marrow involvement of granulocytic sarcoma was suspected. Her chromosome study repeatedly revealed a 46,XX,t(5;12)(q13;p13) karyotype. Case reports of t(5;12)(q13;p13) are extremely rare in the literature. To our knowledge, this is the first report of t(5;12)(q13;p13) in a patient with acute myelogenous leukemia with preceding granulocytic sarcoma.

AB - A 56-year-old woman was brought to the emergency room with gum swelling and pain. Biopsy of the gingiva revealed sheet-like proliferation of myeloperoxidase and CD45-positive large cells, and she was diagnosed with granulocytic sarcoma. Two years later, bone marrow involvement of granulocytic sarcoma was suspected. Her chromosome study repeatedly revealed a 46,XX,t(5;12)(q13;p13) karyotype. Case reports of t(5;12)(q13;p13) are extremely rare in the literature. To our knowledge, this is the first report of t(5;12)(q13;p13) in a patient with acute myelogenous leukemia with preceding granulocytic sarcoma.

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