Abstract
Over the past decade, there has been an increasing interest in using nanotechnology for cancer therapy. The development of smart targeted nanoparticles (NPs) that can deliver drugs at a sustained rate directly to cancer cells may provide better efficacy and lower toxicity for treating primary and advanced metastatic tumors. We highlight some of the promising classes of targeting molecules that are under development for the delivery of NPs. We also review the emerging technologies for the fabrication of targeted NPs using microfluidic devices.
| Original language | English |
|---|---|
| Pages (from-to) | 14-21 |
| Number of pages | 8 |
| Journal | Nano Today |
| Volume | 2 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2007 Jun 1 |
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All Science Journal Classification (ASJC) codes
- Biotechnology
- Bioengineering
- Biomedical Engineering
- Materials Science(all)
- Pharmaceutical Science
Cite this
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Targeted nanoparticles for cancer therapy. / Gu, Frank X.; Karnik, Rohit; Wang, Andrew Z.; Alexis, Frank; Levy-Nissenbaum, Etgar; Hong, Seungpyo; Langer, Robert S.; Farokhzad, Omid C.
In: Nano Today, Vol. 2, No. 3, 01.06.2007, p. 14-21.Research output: Contribution to journal › Article
TY - JOUR
T1 - Targeted nanoparticles for cancer therapy
AU - Gu, Frank X.
AU - Karnik, Rohit
AU - Wang, Andrew Z.
AU - Alexis, Frank
AU - Levy-Nissenbaum, Etgar
AU - Hong, Seungpyo
AU - Langer, Robert S.
AU - Farokhzad, Omid C.
PY - 2007/6/1
Y1 - 2007/6/1
N2 - Over the past decade, there has been an increasing interest in using nanotechnology for cancer therapy. The development of smart targeted nanoparticles (NPs) that can deliver drugs at a sustained rate directly to cancer cells may provide better efficacy and lower toxicity for treating primary and advanced metastatic tumors. We highlight some of the promising classes of targeting molecules that are under development for the delivery of NPs. We also review the emerging technologies for the fabrication of targeted NPs using microfluidic devices.
AB - Over the past decade, there has been an increasing interest in using nanotechnology for cancer therapy. The development of smart targeted nanoparticles (NPs) that can deliver drugs at a sustained rate directly to cancer cells may provide better efficacy and lower toxicity for treating primary and advanced metastatic tumors. We highlight some of the promising classes of targeting molecules that are under development for the delivery of NPs. We also review the emerging technologies for the fabrication of targeted NPs using microfluidic devices.
UR - http://www.scopus.com/inward/record.url?scp=34247642609&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34247642609&partnerID=8YFLogxK
U2 - 10.1016/S1748-0132(07)70083-X
DO - 10.1016/S1748-0132(07)70083-X
M3 - Article
AN - SCOPUS:34247642609
VL - 2
SP - 14
EP - 21
JO - Nano Today
JF - Nano Today
SN - 1748-0132
IS - 3
ER -