Targeted nanoparticles for cancer therapy

Frank X. Gu, Rohit Karnik, Andrew Z. Wang, Frank Alexis, Etgar Levy-Nissenbaum, Seungpyo Hong, Robert S. Langer, Omid C. Farokhzad

Research output: Contribution to journalArticle

391 Citations (Scopus)

Abstract

Over the past decade, there has been an increasing interest in using nanotechnology for cancer therapy. The development of smart targeted nanoparticles (NPs) that can deliver drugs at a sustained rate directly to cancer cells may provide better efficacy and lower toxicity for treating primary and advanced metastatic tumors. We highlight some of the promising classes of targeting molecules that are under development for the delivery of NPs. We also review the emerging technologies for the fabrication of targeted NPs using microfluidic devices.

Original languageEnglish
Pages (from-to)14-21
Number of pages8
JournalNano Today
Volume2
Issue number3
DOIs
Publication statusPublished - 2007 Jun 1

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Nanoparticles
Lab-On-A-Chip Devices
Neoplasms
Nanotechnology
Microfluidics
Toxicity
Tumors
Therapeutics
Cells
Technology
Fabrication
Molecules
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering
  • Materials Science(all)
  • Pharmaceutical Science

Cite this

Gu, F. X., Karnik, R., Wang, A. Z., Alexis, F., Levy-Nissenbaum, E., Hong, S., ... Farokhzad, O. C. (2007). Targeted nanoparticles for cancer therapy. Nano Today, 2(3), 14-21. https://doi.org/10.1016/S1748-0132(07)70083-X
Gu, Frank X. ; Karnik, Rohit ; Wang, Andrew Z. ; Alexis, Frank ; Levy-Nissenbaum, Etgar ; Hong, Seungpyo ; Langer, Robert S. ; Farokhzad, Omid C. / Targeted nanoparticles for cancer therapy. In: Nano Today. 2007 ; Vol. 2, No. 3. pp. 14-21.
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Gu, FX, Karnik, R, Wang, AZ, Alexis, F, Levy-Nissenbaum, E, Hong, S, Langer, RS & Farokhzad, OC 2007, 'Targeted nanoparticles for cancer therapy', Nano Today, vol. 2, no. 3, pp. 14-21. https://doi.org/10.1016/S1748-0132(07)70083-X

Targeted nanoparticles for cancer therapy. / Gu, Frank X.; Karnik, Rohit; Wang, Andrew Z.; Alexis, Frank; Levy-Nissenbaum, Etgar; Hong, Seungpyo; Langer, Robert S.; Farokhzad, Omid C.

In: Nano Today, Vol. 2, No. 3, 01.06.2007, p. 14-21.

Research output: Contribution to journalArticle

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Gu FX, Karnik R, Wang AZ, Alexis F, Levy-Nissenbaum E, Hong S et al. Targeted nanoparticles for cancer therapy. Nano Today. 2007 Jun 1;2(3):14-21. https://doi.org/10.1016/S1748-0132(07)70083-X