Abstract
The present study was undertaken to evaluate effects of dietary taurine supplementation on the homeostasis of trace elements, including Se, Cu, Mn and Cr, in rats chronically consuming alcohol. Male SD rats were fed for 8 wk a liquid form of a control diet (CD), an ethanol diet (ED), or a taurine-supplemented ethanol diet (TED). Plasma Se and Mn concentrations were significantly lower in the ED rats than in the CD rats; dietary taurine supplementation corrected alcohol-induced decreases in plasma Se and Mn levels. Chronic alcohol consumption significantly increased urinary excretion of Se (a 53% increase, p<0.05), Cr (a 62% increase, p<0.05), Mn (a 45% increase, p<0.05) and Cu (a 30% increase, p<0.05) in rats. Urinary losses of these trace elements induced by chronic alcohol consumption in rats were abolished by taurine supplementation. These results suggest that taurine supplementation in rats may protect against Se, Cr and Mn insufficiency caused by chronic alcohol-mediated loss of the trace elements in the urine.
| Original language | English |
|---|---|
| Title of host publication | Taurine 7 |
| Pages | 407-414 |
| Number of pages | 8 |
| DOIs | |
| Publication status | Published - 2009 Apr 22 |
Publication series
| Name | Advances in Experimental Medicine and Biology |
|---|---|
| Volume | 643 |
| ISSN (Print) | 0065-2598 |
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All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)
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Taurine normalizes blood levels and urinary loss of selenium, chromium, and manganese in rats chronically consuming alcohol. / Park, Taesun; Cho, Keunsook; Park, Sung Hee; Lee, Dong Hee; Kim, Ha Won.
Taurine 7. 2009. p. 407-414 (Advances in Experimental Medicine and Biology; Vol. 643).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
TY - GEN
T1 - Taurine normalizes blood levels and urinary loss of selenium, chromium, and manganese in rats chronically consuming alcohol
AU - Park, Taesun
AU - Cho, Keunsook
AU - Park, Sung Hee
AU - Lee, Dong Hee
AU - Kim, Ha Won
PY - 2009/4/22
Y1 - 2009/4/22
N2 - The present study was undertaken to evaluate effects of dietary taurine supplementation on the homeostasis of trace elements, including Se, Cu, Mn and Cr, in rats chronically consuming alcohol. Male SD rats were fed for 8 wk a liquid form of a control diet (CD), an ethanol diet (ED), or a taurine-supplemented ethanol diet (TED). Plasma Se and Mn concentrations were significantly lower in the ED rats than in the CD rats; dietary taurine supplementation corrected alcohol-induced decreases in plasma Se and Mn levels. Chronic alcohol consumption significantly increased urinary excretion of Se (a 53% increase, p<0.05), Cr (a 62% increase, p<0.05), Mn (a 45% increase, p<0.05) and Cu (a 30% increase, p<0.05) in rats. Urinary losses of these trace elements induced by chronic alcohol consumption in rats were abolished by taurine supplementation. These results suggest that taurine supplementation in rats may protect against Se, Cr and Mn insufficiency caused by chronic alcohol-mediated loss of the trace elements in the urine.
AB - The present study was undertaken to evaluate effects of dietary taurine supplementation on the homeostasis of trace elements, including Se, Cu, Mn and Cr, in rats chronically consuming alcohol. Male SD rats were fed for 8 wk a liquid form of a control diet (CD), an ethanol diet (ED), or a taurine-supplemented ethanol diet (TED). Plasma Se and Mn concentrations were significantly lower in the ED rats than in the CD rats; dietary taurine supplementation corrected alcohol-induced decreases in plasma Se and Mn levels. Chronic alcohol consumption significantly increased urinary excretion of Se (a 53% increase, p<0.05), Cr (a 62% increase, p<0.05), Mn (a 45% increase, p<0.05) and Cu (a 30% increase, p<0.05) in rats. Urinary losses of these trace elements induced by chronic alcohol consumption in rats were abolished by taurine supplementation. These results suggest that taurine supplementation in rats may protect against Se, Cr and Mn insufficiency caused by chronic alcohol-mediated loss of the trace elements in the urine.
UR - http://www.scopus.com/inward/record.url?scp=63149098886&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=63149098886&partnerID=8YFLogxK
U2 - 10.1007/978-0-387-75681-3_42
DO - 10.1007/978-0-387-75681-3_42
M3 - Conference contribution
C2 - 19239172
AN - SCOPUS:63149098886
SN - 9780387756806
T3 - Advances in Experimental Medicine and Biology
SP - 407
EP - 414
BT - Taurine 7
ER -