Taurine normalizes blood levels and urinary loss of selenium, chromium, and manganese in rats chronically consuming alcohol

Taesun Park, Keunsook Cho, Sung Hee Park, Dong Hee Lee, Ha Won Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

The present study was undertaken to evaluate effects of dietary taurine supplementation on the homeostasis of trace elements, including Se, Cu, Mn and Cr, in rats chronically consuming alcohol. Male SD rats were fed for 8 wk a liquid form of a control diet (CD), an ethanol diet (ED), or a taurine-supplemented ethanol diet (TED). Plasma Se and Mn concentrations were significantly lower in the ED rats than in the CD rats; dietary taurine supplementation corrected alcohol-induced decreases in plasma Se and Mn levels. Chronic alcohol consumption significantly increased urinary excretion of Se (a 53% increase, p<0.05), Cr (a 62% increase, p<0.05), Mn (a 45% increase, p<0.05) and Cu (a 30% increase, p<0.05) in rats. Urinary losses of these trace elements induced by chronic alcohol consumption in rats were abolished by taurine supplementation. These results suggest that taurine supplementation in rats may protect against Se, Cr and Mn insufficiency caused by chronic alcohol-mediated loss of the trace elements in the urine.

Original languageEnglish
Title of host publicationTaurine 7
Pages407-414
Number of pages8
DOIs
Publication statusPublished - 2009 Apr 22

Publication series

NameAdvances in Experimental Medicine and Biology
Volume643
ISSN (Print)0065-2598

Fingerprint

Taurine
Chromium
Manganese
Selenium
Rats
Blood
Nutrition
Alcohols
Diet
Trace Elements
Ethanol
Dietary Supplements
Alcohol Drinking
Plasmas
Homeostasis
Urine
Liquids

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Park, T., Cho, K., Park, S. H., Lee, D. H., & Kim, H. W. (2009). Taurine normalizes blood levels and urinary loss of selenium, chromium, and manganese in rats chronically consuming alcohol. In Taurine 7 (pp. 407-414). (Advances in Experimental Medicine and Biology; Vol. 643). https://doi.org/10.1007/978-0-387-75681-3_42
Park, Taesun ; Cho, Keunsook ; Park, Sung Hee ; Lee, Dong Hee ; Kim, Ha Won. / Taurine normalizes blood levels and urinary loss of selenium, chromium, and manganese in rats chronically consuming alcohol. Taurine 7. 2009. pp. 407-414 (Advances in Experimental Medicine and Biology).
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Park, T, Cho, K, Park, SH, Lee, DH & Kim, HW 2009, Taurine normalizes blood levels and urinary loss of selenium, chromium, and manganese in rats chronically consuming alcohol. in Taurine 7. Advances in Experimental Medicine and Biology, vol. 643, pp. 407-414. https://doi.org/10.1007/978-0-387-75681-3_42

Taurine normalizes blood levels and urinary loss of selenium, chromium, and manganese in rats chronically consuming alcohol. / Park, Taesun; Cho, Keunsook; Park, Sung Hee; Lee, Dong Hee; Kim, Ha Won.

Taurine 7. 2009. p. 407-414 (Advances in Experimental Medicine and Biology; Vol. 643).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Park T, Cho K, Park SH, Lee DH, Kim HW. Taurine normalizes blood levels and urinary loss of selenium, chromium, and manganese in rats chronically consuming alcohol. In Taurine 7. 2009. p. 407-414. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-0-387-75681-3_42