Temperature-corrected fluidic glucose sensor based on microwave resonator

Chorom Jang; Jin Kwan Park; Hee Jo Lee; Gi Ho Yun; Jong Gwan Yook

doi:10.3390/s18113850

Temperature-corrected fluidic glucose sensor based on microwave resonator

Chorom Jang, Jin Kwan Park, Hee Jo Lee, Gi Ho Yun, Jong Gwan Yook

Department of Electrical and Electronic Engineering

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

In this paper, a fluidic glucose sensor that is based on a complementary split-ring resonator (CSRR) is proposed for the microwave frequency region. The detection of glucose with different concentrations from 0 mg/dL to 400 mg/dL in a non-invasive manner is possible by introducing a fluidic system. The glucose concentration can be continuously monitored by tracking the transmission coefficient S₂₁ as a sensing parameter. The variation tendency in S₂₁ by the glucose concentration is analyzed with equivalent circuit model. In addition, to eradicate the systematic error due to temperature variation, the sensor is tested in two temperature conditions: the constant temperature condition and the time-dependent varying temperature condition. For the varying temperature condition, the temperature correction function was derived between the temperature and the variation in S₂₁ for DI water. By applying the fitting function to glucose solution, the subsidiary results due to temperature can be completely eliminated. As a result, the S₂₁ varies by 0.03 dB as the glucose concentration increases from 0 mg/dL to 400 mg/dL.

Original language	English
Article number	3850
Journal	Sensors (Switzerland)
Volume	18
Issue number	11
DOIs	https://doi.org/10.3390/s18113850
Publication status	Published - 2018 Nov 9

Bibliographical note

Funding Information:
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (NRF-2017R1A2B2011724). This research was also supported by the MSIP (Ministry of Science, ICT and Future Planning), Korea, under the ITRC (Information Technology Research Center) support program (IITP-2017-2013-0-00680) supervised by the IITP (Institute for Information and Communications Technology Promotion).

Publisher Copyright:
© 2018 by the authors. Licensee MDPI, Basel, Switzerland.

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Biochemistry
Atomic and Molecular Physics, and Optics
Instrumentation
Electrical and Electronic Engineering

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abstract = "In this paper, a fluidic glucose sensor that is based on a complementary split-ring resonator (CSRR) is proposed for the microwave frequency region. The detection of glucose with different concentrations from 0 mg/dL to 400 mg/dL in a non-invasive manner is possible by introducing a fluidic system. The glucose concentration can be continuously monitored by tracking the transmission coefficient S21 as a sensing parameter. The variation tendency in S21 by the glucose concentration is analyzed with equivalent circuit model. In addition, to eradicate the systematic error due to temperature variation, the sensor is tested in two temperature conditions: the constant temperature condition and the time-dependent varying temperature condition. For the varying temperature condition, the temperature correction function was derived between the temperature and the variation in S21 for DI water. By applying the fitting function to glucose solution, the subsidiary results due to temperature can be completely eliminated. As a result, the S21 varies by 0.03 dB as the glucose concentration increases from 0 mg/dL to 400 mg/dL.",

author = "Chorom Jang and Park, {Jin Kwan} and Lee, {Hee Jo} and Yun, {Gi Ho} and Yook, {Jong Gwan}",

note = "Funding Information: This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (NRF-2017R1A2B2011724). This research was also supported by the MSIP (Ministry of Science, ICT and Future Planning), Korea, under the ITRC (Information Technology Research Center) support program (IITP-2017-2013-0-00680) supervised by the IITP (Institute for Information and Communications Technology Promotion). Publisher Copyright: {\textcopyright} 2018 by the authors. Licensee MDPI, Basel, Switzerland.",

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N1 - Funding Information: This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (NRF-2017R1A2B2011724). This research was also supported by the MSIP (Ministry of Science, ICT and Future Planning), Korea, under the ITRC (Information Technology Research Center) support program (IITP-2017-2013-0-00680) supervised by the IITP (Institute for Information and Communications Technology Promotion). Publisher Copyright: © 2018 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2018/11/9

Y1 - 2018/11/9

N2 - In this paper, a fluidic glucose sensor that is based on a complementary split-ring resonator (CSRR) is proposed for the microwave frequency region. The detection of glucose with different concentrations from 0 mg/dL to 400 mg/dL in a non-invasive manner is possible by introducing a fluidic system. The glucose concentration can be continuously monitored by tracking the transmission coefficient S21 as a sensing parameter. The variation tendency in S21 by the glucose concentration is analyzed with equivalent circuit model. In addition, to eradicate the systematic error due to temperature variation, the sensor is tested in two temperature conditions: the constant temperature condition and the time-dependent varying temperature condition. For the varying temperature condition, the temperature correction function was derived between the temperature and the variation in S21 for DI water. By applying the fitting function to glucose solution, the subsidiary results due to temperature can be completely eliminated. As a result, the S21 varies by 0.03 dB as the glucose concentration increases from 0 mg/dL to 400 mg/dL.

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Temperature-corrected fluidic glucose sensor based on microwave resonator

Abstract

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