Abstract
We have measured the temperature dependence of the capacitance on the poly(dA), poly(dA)-poly(dT), and DNA solutions with both A-T and G-C base pairs to investigate the relation between the capacitance and the DNA structure. As the temperature increases, the capacitance of the single-stranded DNA solution increases, whereas that of the double-stranded one decreases with increasing the temperature and exhibits an upturn when DNA molecules are denatured. Moreover, the temperature dependence of the capacitance is found to be different depending on the DNA sequence. These results suggest that the conformational change of DNA molecules can be detected through the capacitance measurements that do not require any labeling and immobilization on a solid support.
| Original language | English |
|---|---|
| Pages (from-to) | 935-937 |
| Number of pages | 3 |
| Journal | Materials Science and Engineering C |
| Volume | 26 |
| Issue number | 5-7 |
| DOIs | |
| Publication status | Published - 2006 Jul 1 |
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All Science Journal Classification (ASJC) codes
- Biomaterials
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Temperature dependence of capacitance on DNA solutions. / Kim, K. E.; Suck, S. D.; Sohn, M. S.; Kang, B. K.; Yoo, Kyung-hwa.
In: Materials Science and Engineering C, Vol. 26, No. 5-7, 01.07.2006, p. 935-937.Research output: Contribution to journal › Article
TY - JOUR
T1 - Temperature dependence of capacitance on DNA solutions
AU - Kim, K. E.
AU - Suck, S. D.
AU - Sohn, M. S.
AU - Kang, B. K.
AU - Yoo, Kyung-hwa
PY - 2006/7/1
Y1 - 2006/7/1
N2 - We have measured the temperature dependence of the capacitance on the poly(dA), poly(dA)-poly(dT), and DNA solutions with both A-T and G-C base pairs to investigate the relation between the capacitance and the DNA structure. As the temperature increases, the capacitance of the single-stranded DNA solution increases, whereas that of the double-stranded one decreases with increasing the temperature and exhibits an upturn when DNA molecules are denatured. Moreover, the temperature dependence of the capacitance is found to be different depending on the DNA sequence. These results suggest that the conformational change of DNA molecules can be detected through the capacitance measurements that do not require any labeling and immobilization on a solid support.
AB - We have measured the temperature dependence of the capacitance on the poly(dA), poly(dA)-poly(dT), and DNA solutions with both A-T and G-C base pairs to investigate the relation between the capacitance and the DNA structure. As the temperature increases, the capacitance of the single-stranded DNA solution increases, whereas that of the double-stranded one decreases with increasing the temperature and exhibits an upturn when DNA molecules are denatured. Moreover, the temperature dependence of the capacitance is found to be different depending on the DNA sequence. These results suggest that the conformational change of DNA molecules can be detected through the capacitance measurements that do not require any labeling and immobilization on a solid support.
UR - http://www.scopus.com/inward/record.url?scp=33646825030&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33646825030&partnerID=8YFLogxK
U2 - 10.1016/j.msec.2005.09.085
DO - 10.1016/j.msec.2005.09.085
M3 - Article
AN - SCOPUS:33646825030
VL - 26
SP - 935
EP - 937
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
SN - 0928-4931
IS - 5-7
ER -