Temperature dependence of capacitance on DNA solutions

K. E. Kim, S. D. Suck, M. S. Sohn, B. K. Kang, Kyung-hwa Yoo

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We have measured the temperature dependence of the capacitance on the poly(dA), poly(dA)-poly(dT), and DNA solutions with both A-T and G-C base pairs to investigate the relation between the capacitance and the DNA structure. As the temperature increases, the capacitance of the single-stranded DNA solution increases, whereas that of the double-stranded one decreases with increasing the temperature and exhibits an upturn when DNA molecules are denatured. Moreover, the temperature dependence of the capacitance is found to be different depending on the DNA sequence. These results suggest that the conformational change of DNA molecules can be detected through the capacitance measurements that do not require any labeling and immobilization on a solid support.

Original languageEnglish
Pages (from-to)935-937
Number of pages3
JournalMaterials Science and Engineering C
Volume26
Issue number5-7
DOIs
Publication statusPublished - 2006 Jul 1

Fingerprint

DNA
Capacitance
deoxyribonucleic acid
capacitance
temperature dependence
Temperature
Molecules
Capacitance measurement
Single-Stranded DNA
DNA sequences
Labeling
immobilization
marking
molecules
temperature

All Science Journal Classification (ASJC) codes

  • Biomaterials

Cite this

Kim, K. E. ; Suck, S. D. ; Sohn, M. S. ; Kang, B. K. ; Yoo, Kyung-hwa. / Temperature dependence of capacitance on DNA solutions. In: Materials Science and Engineering C. 2006 ; Vol. 26, No. 5-7. pp. 935-937.
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Temperature dependence of capacitance on DNA solutions. / Kim, K. E.; Suck, S. D.; Sohn, M. S.; Kang, B. K.; Yoo, Kyung-hwa.

In: Materials Science and Engineering C, Vol. 26, No. 5-7, 01.07.2006, p. 935-937.

Research output: Contribution to journalArticle

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AU - Kim, K. E.

AU - Suck, S. D.

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AB - We have measured the temperature dependence of the capacitance on the poly(dA), poly(dA)-poly(dT), and DNA solutions with both A-T and G-C base pairs to investigate the relation between the capacitance and the DNA structure. As the temperature increases, the capacitance of the single-stranded DNA solution increases, whereas that of the double-stranded one decreases with increasing the temperature and exhibits an upturn when DNA molecules are denatured. Moreover, the temperature dependence of the capacitance is found to be different depending on the DNA sequence. These results suggest that the conformational change of DNA molecules can be detected through the capacitance measurements that do not require any labeling and immobilization on a solid support.

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