Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model

Young Bin Ji, Sang Hoon Kim, Kiyoung Jeong, Yuna Choi, Joo Hiuk Son, Dong Woo Park, Sam Kyu Noh, Tae In Jeon, Yong Min Huh, Seungjoo Haam, Sang Kil Lee, Seung Jae Oh, Jin Suck Suh

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Abstract

We have investigated basic properties of normal gastrointestinal (GI) tract tissues, including glandular stomach (GS), fore stomach (FS), large intestine (LI), small intestine (SI), and esophagus (ESO), from a rat model using terahertz (THz) reflection imaging and spectroscopy. The THz images collected from stratified squamous epithelia (SSE) of FS and ESO show a lower peak-to-peak value compared to those from columnar epithelia (CE) of GS, LI, or SI because the SSE contains less water than CE. The refractive index and absorption coefficient of FS were less than those of GS or LI, both having values similar to those of water. Additionally, we report internal reflection THz signals from ESO, although we were unable to determine the exact interface for this internal reflection.

Original languageEnglish
Article numberA4162
Pages (from-to)4162-4170
Number of pages9
JournalBiomedical Optics Express
Volume5
Issue number12
DOIs
Publication statusPublished - 2014 Jan 1

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All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

Cite this

Ji, Y. B., Kim, S. H., Jeong, K., Choi, Y., Son, J. H., Park, D. W., Noh, S. K., Jeon, T. I., Huh, Y. M., Haam, S., Lee, S. K., Oh, S. J., & Suh, J. S. (2014). Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model. Biomedical Optics Express, 5(12), 4162-4170. [A4162]. https://doi.org/10.1364/BOE.5.004162