Abstract
Background: Terminal QRS complex distortion on admission is a simple and reliable predictor of infarct size in patients with acute myocardial infarction (AMI). It is uncertain, however, whether this reflects reduced myocardial perfusion of the infarct area and a larger area of the myocardium at risk. This study was conducted to investigate whether terminal QRS distortion complex on admission is a reliable predictor of reduced residual flow and a larger area of the myocardium at risk compared to patients who are admitted without a terminal QRS distortion. Methods: We evaluated the relationship between terminal QRS complex distortion and residual flow to the infarct zone and risk area in 46 anterior AMI patients undergoing primary angioplasty. 99mTc-sestamibi imaging was performed at baseline and 5-9 days after angioplasty. The study population was divided into those with (Group I, n=16) and without (Group II, n=30) terminal QRS complex distortion. Results: Baseline characteristics were similar between the two groups. The area of the myocardium at risk was higher in Group I (59.9±15.3%) than in Group II (48.6±13.7%, p<0.05; mean+SD) while the nadir measurement of the residual flow was lower in Group I (0.10±0.07) than in Group II (0.16±0.09, p<0.05). Although the final infarct size was significantly higher in Group I (40.8±17.2%) than in Group II (27.1±18.1%, p<0.05), the myocardial salvage index did not differ significantly between the two groups. Conclusion: Terminal QRS complex distortion seems to be associated with less residual flow to the infarct zone, a larger risk area and greater infarct size in patients with anterior AMI.
| Original language | English |
|---|---|
| Pages (from-to) | 21-25 |
| Number of pages | 5 |
| Journal | Korean Journal of Internal Medicine |
| Volume | 20 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2005 Mar |
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All Science Journal Classification (ASJC) codes
- Internal Medicine
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Terminal QRS complex distortion on the admission electrocardiogram in anterior acute myocardial infarction and association with residual flow and infarct size after primary angioplasty. / Yang, Hyun Suk; Lee, Cheol Whan; Hong, Myeong Ki; Moon, Dae Hyuk; Kim, Young Hak; Lee, Sang Gon; Han, Ki Hoon; Kim, Jae Joong; Park, Seong Wook; Park, Seung Jung.
In: Korean Journal of Internal Medicine, Vol. 20, No. 1, 03.2005, p. 21-25.Research output: Contribution to journal › Article
TY - JOUR
T1 - Terminal QRS complex distortion on the admission electrocardiogram in anterior acute myocardial infarction and association with residual flow and infarct size after primary angioplasty
AU - Yang, Hyun Suk
AU - Lee, Cheol Whan
AU - Hong, Myeong Ki
AU - Moon, Dae Hyuk
AU - Kim, Young Hak
AU - Lee, Sang Gon
AU - Han, Ki Hoon
AU - Kim, Jae Joong
AU - Park, Seong Wook
AU - Park, Seung Jung
PY - 2005/3
Y1 - 2005/3
N2 - Background: Terminal QRS complex distortion on admission is a simple and reliable predictor of infarct size in patients with acute myocardial infarction (AMI). It is uncertain, however, whether this reflects reduced myocardial perfusion of the infarct area and a larger area of the myocardium at risk. This study was conducted to investigate whether terminal QRS distortion complex on admission is a reliable predictor of reduced residual flow and a larger area of the myocardium at risk compared to patients who are admitted without a terminal QRS distortion. Methods: We evaluated the relationship between terminal QRS complex distortion and residual flow to the infarct zone and risk area in 46 anterior AMI patients undergoing primary angioplasty. 99mTc-sestamibi imaging was performed at baseline and 5-9 days after angioplasty. The study population was divided into those with (Group I, n=16) and without (Group II, n=30) terminal QRS complex distortion. Results: Baseline characteristics were similar between the two groups. The area of the myocardium at risk was higher in Group I (59.9±15.3%) than in Group II (48.6±13.7%, p<0.05; mean+SD) while the nadir measurement of the residual flow was lower in Group I (0.10±0.07) than in Group II (0.16±0.09, p<0.05). Although the final infarct size was significantly higher in Group I (40.8±17.2%) than in Group II (27.1±18.1%, p<0.05), the myocardial salvage index did not differ significantly between the two groups. Conclusion: Terminal QRS complex distortion seems to be associated with less residual flow to the infarct zone, a larger risk area and greater infarct size in patients with anterior AMI.
AB - Background: Terminal QRS complex distortion on admission is a simple and reliable predictor of infarct size in patients with acute myocardial infarction (AMI). It is uncertain, however, whether this reflects reduced myocardial perfusion of the infarct area and a larger area of the myocardium at risk. This study was conducted to investigate whether terminal QRS distortion complex on admission is a reliable predictor of reduced residual flow and a larger area of the myocardium at risk compared to patients who are admitted without a terminal QRS distortion. Methods: We evaluated the relationship between terminal QRS complex distortion and residual flow to the infarct zone and risk area in 46 anterior AMI patients undergoing primary angioplasty. 99mTc-sestamibi imaging was performed at baseline and 5-9 days after angioplasty. The study population was divided into those with (Group I, n=16) and without (Group II, n=30) terminal QRS complex distortion. Results: Baseline characteristics were similar between the two groups. The area of the myocardium at risk was higher in Group I (59.9±15.3%) than in Group II (48.6±13.7%, p<0.05; mean+SD) while the nadir measurement of the residual flow was lower in Group I (0.10±0.07) than in Group II (0.16±0.09, p<0.05). Although the final infarct size was significantly higher in Group I (40.8±17.2%) than in Group II (27.1±18.1%, p<0.05), the myocardial salvage index did not differ significantly between the two groups. Conclusion: Terminal QRS complex distortion seems to be associated with less residual flow to the infarct zone, a larger risk area and greater infarct size in patients with anterior AMI.
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U2 - 10.3904/kjim.2005.20.1.21
DO - 10.3904/kjim.2005.20.1.21
M3 - Article
C2 - 15906949
AN - SCOPUS:21144458767
VL - 20
SP - 21
EP - 25
JO - Korean Journal of Internal Medicine
JF - Korean Journal of Internal Medicine
SN - 1226-3303
IS - 1
ER -