Terminal QRS complex distortion on the admission electrocardiogram in anterior acute myocardial infarction and association with residual flow and infarct size after primary angioplasty

Hyun Suk Yang, Cheol Whan Lee, Myeong Ki Hong, Dae Hyuk Moon, Young Hak Kim, Sang Gon Lee, Ki Hoon Han, Jae Joong Kim, Seong Wook Park, Seung Jung Park

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Abstract

Background: Terminal QRS complex distortion on admission is a simple and reliable predictor of infarct size in patients with acute myocardial infarction (AMI). It is uncertain, however, whether this reflects reduced myocardial perfusion of the infarct area and a larger area of the myocardium at risk. This study was conducted to investigate whether terminal QRS distortion complex on admission is a reliable predictor of reduced residual flow and a larger area of the myocardium at risk compared to patients who are admitted without a terminal QRS distortion. Methods: We evaluated the relationship between terminal QRS complex distortion and residual flow to the infarct zone and risk area in 46 anterior AMI patients undergoing primary angioplasty. 99mTc-sestamibi imaging was performed at baseline and 5-9 days after angioplasty. The study population was divided into those with (Group I, n=16) and without (Group II, n=30) terminal QRS complex distortion. Results: Baseline characteristics were similar between the two groups. The area of the myocardium at risk was higher in Group I (59.9±15.3%) than in Group II (48.6±13.7%, p<0.05; mean+SD) while the nadir measurement of the residual flow was lower in Group I (0.10±0.07) than in Group II (0.16±0.09, p<0.05). Although the final infarct size was significantly higher in Group I (40.8±17.2%) than in Group II (27.1±18.1%, p<0.05), the myocardial salvage index did not differ significantly between the two groups. Conclusion: Terminal QRS complex distortion seems to be associated with less residual flow to the infarct zone, a larger risk area and greater infarct size in patients with anterior AMI.

Original languageEnglish
Pages (from-to)21-25
Number of pages5
JournalKorean Journal of Internal Medicine
Volume20
Issue number1
DOIs
Publication statusPublished - 2005 Mar

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Angioplasty
Electrocardiography
Myocardial Infarction
Myocardium
Technetium Tc 99m Sestamibi
Perfusion
Population

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Yang, Hyun Suk ; Lee, Cheol Whan ; Hong, Myeong Ki ; Moon, Dae Hyuk ; Kim, Young Hak ; Lee, Sang Gon ; Han, Ki Hoon ; Kim, Jae Joong ; Park, Seong Wook ; Park, Seung Jung. / Terminal QRS complex distortion on the admission electrocardiogram in anterior acute myocardial infarction and association with residual flow and infarct size after primary angioplasty. In: Korean Journal of Internal Medicine. 2005 ; Vol. 20, No. 1. pp. 21-25.
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title = "Terminal QRS complex distortion on the admission electrocardiogram in anterior acute myocardial infarction and association with residual flow and infarct size after primary angioplasty",
abstract = "Background: Terminal QRS complex distortion on admission is a simple and reliable predictor of infarct size in patients with acute myocardial infarction (AMI). It is uncertain, however, whether this reflects reduced myocardial perfusion of the infarct area and a larger area of the myocardium at risk. This study was conducted to investigate whether terminal QRS distortion complex on admission is a reliable predictor of reduced residual flow and a larger area of the myocardium at risk compared to patients who are admitted without a terminal QRS distortion. Methods: We evaluated the relationship between terminal QRS complex distortion and residual flow to the infarct zone and risk area in 46 anterior AMI patients undergoing primary angioplasty. 99mTc-sestamibi imaging was performed at baseline and 5-9 days after angioplasty. The study population was divided into those with (Group I, n=16) and without (Group II, n=30) terminal QRS complex distortion. Results: Baseline characteristics were similar between the two groups. The area of the myocardium at risk was higher in Group I (59.9±15.3{\%}) than in Group II (48.6±13.7{\%}, p<0.05; mean+SD) while the nadir measurement of the residual flow was lower in Group I (0.10±0.07) than in Group II (0.16±0.09, p<0.05). Although the final infarct size was significantly higher in Group I (40.8±17.2{\%}) than in Group II (27.1±18.1{\%}, p<0.05), the myocardial salvage index did not differ significantly between the two groups. Conclusion: Terminal QRS complex distortion seems to be associated with less residual flow to the infarct zone, a larger risk area and greater infarct size in patients with anterior AMI.",
author = "Yang, {Hyun Suk} and Lee, {Cheol Whan} and Hong, {Myeong Ki} and Moon, {Dae Hyuk} and Kim, {Young Hak} and Lee, {Sang Gon} and Han, {Ki Hoon} and Kim, {Jae Joong} and Park, {Seong Wook} and Park, {Seung Jung}",
year = "2005",
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Terminal QRS complex distortion on the admission electrocardiogram in anterior acute myocardial infarction and association with residual flow and infarct size after primary angioplasty. / Yang, Hyun Suk; Lee, Cheol Whan; Hong, Myeong Ki; Moon, Dae Hyuk; Kim, Young Hak; Lee, Sang Gon; Han, Ki Hoon; Kim, Jae Joong; Park, Seong Wook; Park, Seung Jung.

In: Korean Journal of Internal Medicine, Vol. 20, No. 1, 03.2005, p. 21-25.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Terminal QRS complex distortion on the admission electrocardiogram in anterior acute myocardial infarction and association with residual flow and infarct size after primary angioplasty

AU - Yang, Hyun Suk

AU - Lee, Cheol Whan

AU - Hong, Myeong Ki

AU - Moon, Dae Hyuk

AU - Kim, Young Hak

AU - Lee, Sang Gon

AU - Han, Ki Hoon

AU - Kim, Jae Joong

AU - Park, Seong Wook

AU - Park, Seung Jung

PY - 2005/3

Y1 - 2005/3

N2 - Background: Terminal QRS complex distortion on admission is a simple and reliable predictor of infarct size in patients with acute myocardial infarction (AMI). It is uncertain, however, whether this reflects reduced myocardial perfusion of the infarct area and a larger area of the myocardium at risk. This study was conducted to investigate whether terminal QRS distortion complex on admission is a reliable predictor of reduced residual flow and a larger area of the myocardium at risk compared to patients who are admitted without a terminal QRS distortion. Methods: We evaluated the relationship between terminal QRS complex distortion and residual flow to the infarct zone and risk area in 46 anterior AMI patients undergoing primary angioplasty. 99mTc-sestamibi imaging was performed at baseline and 5-9 days after angioplasty. The study population was divided into those with (Group I, n=16) and without (Group II, n=30) terminal QRS complex distortion. Results: Baseline characteristics were similar between the two groups. The area of the myocardium at risk was higher in Group I (59.9±15.3%) than in Group II (48.6±13.7%, p<0.05; mean+SD) while the nadir measurement of the residual flow was lower in Group I (0.10±0.07) than in Group II (0.16±0.09, p<0.05). Although the final infarct size was significantly higher in Group I (40.8±17.2%) than in Group II (27.1±18.1%, p<0.05), the myocardial salvage index did not differ significantly between the two groups. Conclusion: Terminal QRS complex distortion seems to be associated with less residual flow to the infarct zone, a larger risk area and greater infarct size in patients with anterior AMI.

AB - Background: Terminal QRS complex distortion on admission is a simple and reliable predictor of infarct size in patients with acute myocardial infarction (AMI). It is uncertain, however, whether this reflects reduced myocardial perfusion of the infarct area and a larger area of the myocardium at risk. This study was conducted to investigate whether terminal QRS distortion complex on admission is a reliable predictor of reduced residual flow and a larger area of the myocardium at risk compared to patients who are admitted without a terminal QRS distortion. Methods: We evaluated the relationship between terminal QRS complex distortion and residual flow to the infarct zone and risk area in 46 anterior AMI patients undergoing primary angioplasty. 99mTc-sestamibi imaging was performed at baseline and 5-9 days after angioplasty. The study population was divided into those with (Group I, n=16) and without (Group II, n=30) terminal QRS complex distortion. Results: Baseline characteristics were similar between the two groups. The area of the myocardium at risk was higher in Group I (59.9±15.3%) than in Group II (48.6±13.7%, p<0.05; mean+SD) while the nadir measurement of the residual flow was lower in Group I (0.10±0.07) than in Group II (0.16±0.09, p<0.05). Although the final infarct size was significantly higher in Group I (40.8±17.2%) than in Group II (27.1±18.1%, p<0.05), the myocardial salvage index did not differ significantly between the two groups. Conclusion: Terminal QRS complex distortion seems to be associated with less residual flow to the infarct zone, a larger risk area and greater infarct size in patients with anterior AMI.

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U2 - 10.3904/kjim.2005.20.1.21

DO - 10.3904/kjim.2005.20.1.21

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