The association between arterial stiffness and colorectal adenomatous polyp in women

Hong Bae Kim, Hye Ree Lee, Jae Yong Shim, Ha Young Na, Byoung Jin Park, Dong Hyuk Jung, Yong Jae Lee

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Colorectal adenomatous polyp is a precancerous lesion, and some studies have documented its link with cardiovascular risk factors. This study aimed to investigate the association between arterial stiffness and colorectal adenomatous polyp. Methods: Among 388 Korean women, we examined the association between brachial-ankle pulse wave velocity (baPWV) as a measurement of arterial stiffness and the presence of colorectal adenomatous polyp as determined by colonoscopy. baPWV values were categorized separately as follows: ≤1199cm/s, 1200-1399cm/s, 1400-1599cm/s and ≥1600cm/s. The odds ratios (ORs) and 95% confidence intervals (CIs) for colorectal adenomatous polyp were calculated across each group of PWVs. Results: The prevalence of colorectal adenomatous polyp was 9.5%. After adjusting for age, body mass index (BMI), cigarette smoking, blood pressure, fasting plasma glucose, and triglycerides, the ORs (95% CIs) for colorectal adenomatous polyp according to each of the four groups of baPWV were 1.00, 2.89 (0.52-15.98), 3.27 (0.48-22.24), and 11.17 (1.17-106.99). Conclusions: A higher level of baPWV was found to be independently associated with the presence of colorectal adenomatous polyp, regardless of classic cardiovascular risk factors and other components of metabolic syndrome in women.

Original languageEnglish
Pages (from-to)765-769
Number of pages5
JournalJournal of Women's Health
Volume20
Issue number5
DOIs
Publication statusPublished - 2011 May 1

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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