The association between body mass index and mortality on peritoneal dialysis

A prospective cohort study

Yong Kyun Kim, Su Hyun Kim, Hyung Wook Kim, Young OK Kim, Dong Chan Jin, Ho Chul Song, Euy Jin Choi, Yong Lim Kim, Yon Su Kim, Shin-Wook Kang, Nam Ho Kim, Chul Woo Yang

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

⧫ Background: Previous studies have demonstrated that increased body mass index (BMI) is associated with decreased mortality in hemodialysis (HD) patients. However, the association between BMI and survival has not been well established in patients undergoing peritoneal dialysis (PD). The aim of the study was to determine the association between BMI and mortality in the PD popula¬tion using the Clinical Research Center (CRC) registry for end-stage renal disease (ESRD) cohort in Korea. ⧫ Methods: Prevalent patients with PD were selected from the CRC registry for ESRD, a prospective cohort study on dialysis patients in Korea. Patients were categorized into four groups by quartiles of BMI. Cox regression analysis was used to calculate the adjusted hazard ratio (HR) of mortality with a BMI of quartile 2 (21.4 - 23.5 kg/m2) as the reference. ⧫ Results: Atotalof900prevalentpatientsundergoingPD were included. The median follow-up period was 24 months. The multivariate Cox proportional hazard model showed that the lowest quartile of BMI was associated with higher mor¬tality (HR 3.00,95% confidence interval (Cl), 1.26 - 7.15). However, the higher quartiles of BMI were not associated with mortality compared with the reference category of BMI quartile 2 (Quartile 3: HR 1.11, 95% Cl, 0.43 - 2.85, Quartile 4: HR 1.64, 95% Cl, 0.66-4.06) after adjustment for clinical variables. ⧫ Conclusions: Lower BMI was a significant risk factor for death, but increased BMI was not associated with mortality in Korean PD patients.

Original languageEnglish
Pages (from-to)383-389
Number of pages7
JournalPeritoneal Dialysis International
Volume34
Issue number4
DOIs
Publication statusPublished - 2014 Jan 1

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Peritoneal Dialysis
Body Mass Index
Cohort Studies
Prospective Studies
Mortality
Korea
Chronic Kidney Failure
Registries
Proportional Hazards Models
Research
Renal Dialysis
Dialysis
Regression Analysis
Confidence Intervals
Survival

All Science Journal Classification (ASJC) codes

  • Nephrology

Cite this

Kim, Y. K., Kim, S. H., Kim, H. W., Kim, Y. OK., Jin, D. C., Song, H. C., ... Yang, C. W. (2014). The association between body mass index and mortality on peritoneal dialysis: A prospective cohort study. Peritoneal Dialysis International, 34(4), 383-389. https://doi.org/10.3747/pdi.2013.00008
Kim, Yong Kyun ; Kim, Su Hyun ; Kim, Hyung Wook ; Kim, Young OK ; Jin, Dong Chan ; Song, Ho Chul ; Choi, Euy Jin ; Kim, Yong Lim ; Kim, Yon Su ; Kang, Shin-Wook ; Kim, Nam Ho ; Yang, Chul Woo. / The association between body mass index and mortality on peritoneal dialysis : A prospective cohort study. In: Peritoneal Dialysis International. 2014 ; Vol. 34, No. 4. pp. 383-389.
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abstract = "⧫ Background: Previous studies have demonstrated that increased body mass index (BMI) is associated with decreased mortality in hemodialysis (HD) patients. However, the association between BMI and survival has not been well established in patients undergoing peritoneal dialysis (PD). The aim of the study was to determine the association between BMI and mortality in the PD popula¬tion using the Clinical Research Center (CRC) registry for end-stage renal disease (ESRD) cohort in Korea. ⧫ Methods: Prevalent patients with PD were selected from the CRC registry for ESRD, a prospective cohort study on dialysis patients in Korea. Patients were categorized into four groups by quartiles of BMI. Cox regression analysis was used to calculate the adjusted hazard ratio (HR) of mortality with a BMI of quartile 2 (21.4 - 23.5 kg/m2) as the reference. ⧫ Results: Atotalof900prevalentpatientsundergoingPD were included. The median follow-up period was 24 months. The multivariate Cox proportional hazard model showed that the lowest quartile of BMI was associated with higher mor¬tality (HR 3.00,95{\%} confidence interval (Cl), 1.26 - 7.15). However, the higher quartiles of BMI were not associated with mortality compared with the reference category of BMI quartile 2 (Quartile 3: HR 1.11, 95{\%} Cl, 0.43 - 2.85, Quartile 4: HR 1.64, 95{\%} Cl, 0.66-4.06) after adjustment for clinical variables. ⧫ Conclusions: Lower BMI was a significant risk factor for death, but increased BMI was not associated with mortality in Korean PD patients.",
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Kim, YK, Kim, SH, Kim, HW, Kim, YOK, Jin, DC, Song, HC, Choi, EJ, Kim, YL, Kim, YS, Kang, S-W, Kim, NH & Yang, CW 2014, 'The association between body mass index and mortality on peritoneal dialysis: A prospective cohort study', Peritoneal Dialysis International, vol. 34, no. 4, pp. 383-389. https://doi.org/10.3747/pdi.2013.00008

The association between body mass index and mortality on peritoneal dialysis : A prospective cohort study. / Kim, Yong Kyun; Kim, Su Hyun; Kim, Hyung Wook; Kim, Young OK; Jin, Dong Chan; Song, Ho Chul; Choi, Euy Jin; Kim, Yong Lim; Kim, Yon Su; Kang, Shin-Wook; Kim, Nam Ho; Yang, Chul Woo.

In: Peritoneal Dialysis International, Vol. 34, No. 4, 01.01.2014, p. 383-389.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The association between body mass index and mortality on peritoneal dialysis

T2 - A prospective cohort study

AU - Kim, Yong Kyun

AU - Kim, Su Hyun

AU - Kim, Hyung Wook

AU - Kim, Young OK

AU - Jin, Dong Chan

AU - Song, Ho Chul

AU - Choi, Euy Jin

AU - Kim, Yong Lim

AU - Kim, Yon Su

AU - Kang, Shin-Wook

AU - Kim, Nam Ho

AU - Yang, Chul Woo

PY - 2014/1/1

Y1 - 2014/1/1

N2 - ⧫ Background: Previous studies have demonstrated that increased body mass index (BMI) is associated with decreased mortality in hemodialysis (HD) patients. However, the association between BMI and survival has not been well established in patients undergoing peritoneal dialysis (PD). The aim of the study was to determine the association between BMI and mortality in the PD popula¬tion using the Clinical Research Center (CRC) registry for end-stage renal disease (ESRD) cohort in Korea. ⧫ Methods: Prevalent patients with PD were selected from the CRC registry for ESRD, a prospective cohort study on dialysis patients in Korea. Patients were categorized into four groups by quartiles of BMI. Cox regression analysis was used to calculate the adjusted hazard ratio (HR) of mortality with a BMI of quartile 2 (21.4 - 23.5 kg/m2) as the reference. ⧫ Results: Atotalof900prevalentpatientsundergoingPD were included. The median follow-up period was 24 months. The multivariate Cox proportional hazard model showed that the lowest quartile of BMI was associated with higher mor¬tality (HR 3.00,95% confidence interval (Cl), 1.26 - 7.15). However, the higher quartiles of BMI were not associated with mortality compared with the reference category of BMI quartile 2 (Quartile 3: HR 1.11, 95% Cl, 0.43 - 2.85, Quartile 4: HR 1.64, 95% Cl, 0.66-4.06) after adjustment for clinical variables. ⧫ Conclusions: Lower BMI was a significant risk factor for death, but increased BMI was not associated with mortality in Korean PD patients.

AB - ⧫ Background: Previous studies have demonstrated that increased body mass index (BMI) is associated with decreased mortality in hemodialysis (HD) patients. However, the association between BMI and survival has not been well established in patients undergoing peritoneal dialysis (PD). The aim of the study was to determine the association between BMI and mortality in the PD popula¬tion using the Clinical Research Center (CRC) registry for end-stage renal disease (ESRD) cohort in Korea. ⧫ Methods: Prevalent patients with PD were selected from the CRC registry for ESRD, a prospective cohort study on dialysis patients in Korea. Patients were categorized into four groups by quartiles of BMI. Cox regression analysis was used to calculate the adjusted hazard ratio (HR) of mortality with a BMI of quartile 2 (21.4 - 23.5 kg/m2) as the reference. ⧫ Results: Atotalof900prevalentpatientsundergoingPD were included. The median follow-up period was 24 months. The multivariate Cox proportional hazard model showed that the lowest quartile of BMI was associated with higher mor¬tality (HR 3.00,95% confidence interval (Cl), 1.26 - 7.15). However, the higher quartiles of BMI were not associated with mortality compared with the reference category of BMI quartile 2 (Quartile 3: HR 1.11, 95% Cl, 0.43 - 2.85, Quartile 4: HR 1.64, 95% Cl, 0.66-4.06) after adjustment for clinical variables. ⧫ Conclusions: Lower BMI was a significant risk factor for death, but increased BMI was not associated with mortality in Korean PD patients.

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U2 - 10.3747/pdi.2013.00008

DO - 10.3747/pdi.2013.00008

M3 - Article

VL - 34

SP - 383

EP - 389

JO - Peritoneal Dialysis International

JF - Peritoneal Dialysis International

SN - 0896-8608

IS - 4

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