The association between coronary artery calcification and mean platelet volume in the general population

Dong Hyuk Jung, Hye Ree Lee, Yongjae Lee, Jong Koo Kim, Byung Jin Park, Jae Yong Shim

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Patients with coronary artery calcification have an increased risk of coronary vascular events and mortality. Coronary artery calcification can be quantified using the coronary calcium score (CCS) from multi-detected row computed tomography (MDCT), and the score is proportionally related to the severity of atherosclerotic disease. Mean platelet volume (MPV) is gaining interest as a new independent cardiovascular risk factor. Accordingly, the aim of our study was to evaluate the relationship between CCS and MPV in the general population. A total of 2116 individuals were enrolled from a health promotion center between July 2007 and June 2010. Among them, 259 subjects were included in the final analysis. MDCT was used to measure CCS and CCS>1 was defined as the presence of coronary calcification. The MPV value was significantly higher in the coronary artery calcification group than in the control group. Multivariate analyses showed that MPV was positively associated with coronary calcification (OR, 1.61; 95% CI 1.022.55). In summary, there was a significant association between coronary artery calcification and MPV in the general population. Therefore, the detection of elevated MPV should alert clinicians to the coexistence of multiple underlying CVD risk factors warranting early evaluation and treatment.

Original languageEnglish
Pages (from-to)567-571
Number of pages5
JournalPlatelets
Volume22
Issue number8
DOIs
Publication statusPublished - 2011 Dec 1

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Mean Platelet Volume
Coronary Vessels
Population
Calcium
Tomography
Health Promotion
Blood Vessels
Multivariate Analysis
Control Groups
Mortality

All Science Journal Classification (ASJC) codes

  • Hematology

Cite this

Jung, Dong Hyuk ; Lee, Hye Ree ; Lee, Yongjae ; Kim, Jong Koo ; Park, Byung Jin ; Shim, Jae Yong. / The association between coronary artery calcification and mean platelet volume in the general population. In: Platelets. 2011 ; Vol. 22, No. 8. pp. 567-571.
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The association between coronary artery calcification and mean platelet volume in the general population. / Jung, Dong Hyuk; Lee, Hye Ree; Lee, Yongjae; Kim, Jong Koo; Park, Byung Jin; Shim, Jae Yong.

In: Platelets, Vol. 22, No. 8, 01.12.2011, p. 567-571.

Research output: Contribution to journalArticle

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