Abstract
Objectives: The aim of this study is to investigate the association between obesity indices (body mass index, weight, waist-hip ratio and waist circumference) in adolescents and the carotid intima-media thickness (C-IMT) in early adulthood. We also wanted to identify the best predictor for C-IMT among these obesity indices. Methods: This study used community-based prospective cohort study, known as the Kangwha Study, and the data we used were from subjects who were 16-years old in 1996 (defined as HadolescenceI) and 25 years-old in 2005 (defined as Hearly adulthoodI). The 256 subjects (113 men and 143 women) who were used for analysis participated in both follow-ups, and they underwent B-mode ultrasonography of the carotid arteries at the early adulthood follow-up. Obesity indices were defined as the body mass index, weight, waist-hip ratio and waist circumference. The C-IMT was defined as the mean of the maximal IMT of each common carotid artery. The C-IMT and obesity indices associations were evaluated via multivariable regression, logistic regression and the receiver-operator characteristic curve analyses. Results: In men, all the obesity indices in adolescence were showed to have statistically significant positive association with C-IMT in early adulthood. However, no such relationship was showed in women. On multiple regression and logistic regression analysis, the waist-hip ratio showed the biggest relationship with the C-IMT among the 4 obesity indices. However, there were no statistical significant differences and no best predictor was found. For the women, the obesity incidences and C-IMT showed no relationships. Conclusions: This study suggested that obesity in adolescence was related to an increase C-IMT in healthy young Korean men.
| Original language | English |
|---|---|
| Pages (from-to) | 107-114 |
| Number of pages | 8 |
| Journal | Journal of Preventive Medicine and Public Health |
| Volume | 41 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2008 Mar 1 |
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All Science Journal Classification (ASJC) codes
- Public Health, Environmental and Occupational Health
- Medicine(all)
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The association between obesity indices in adolescence and carotid intima-media thickness in young adults : Kangwha study. / Lee, Yoo Jung; Nam, Chung Mo; Kim, Hyeon Chang; Hur, Nam Wook; Suh, Il.
In: Journal of Preventive Medicine and Public Health, Vol. 41, No. 2, 01.03.2008, p. 107-114.Research output: Contribution to journal › Article
TY - JOUR
T1 - The association between obesity indices in adolescence and carotid intima-media thickness in young adults
T2 - Kangwha study
AU - Lee, Yoo Jung
AU - Nam, Chung Mo
AU - Kim, Hyeon Chang
AU - Hur, Nam Wook
AU - Suh, Il
PY - 2008/3/1
Y1 - 2008/3/1
N2 - Objectives: The aim of this study is to investigate the association between obesity indices (body mass index, weight, waist-hip ratio and waist circumference) in adolescents and the carotid intima-media thickness (C-IMT) in early adulthood. We also wanted to identify the best predictor for C-IMT among these obesity indices. Methods: This study used community-based prospective cohort study, known as the Kangwha Study, and the data we used were from subjects who were 16-years old in 1996 (defined as HadolescenceI) and 25 years-old in 2005 (defined as Hearly adulthoodI). The 256 subjects (113 men and 143 women) who were used for analysis participated in both follow-ups, and they underwent B-mode ultrasonography of the carotid arteries at the early adulthood follow-up. Obesity indices were defined as the body mass index, weight, waist-hip ratio and waist circumference. The C-IMT was defined as the mean of the maximal IMT of each common carotid artery. The C-IMT and obesity indices associations were evaluated via multivariable regression, logistic regression and the receiver-operator characteristic curve analyses. Results: In men, all the obesity indices in adolescence were showed to have statistically significant positive association with C-IMT in early adulthood. However, no such relationship was showed in women. On multiple regression and logistic regression analysis, the waist-hip ratio showed the biggest relationship with the C-IMT among the 4 obesity indices. However, there were no statistical significant differences and no best predictor was found. For the women, the obesity incidences and C-IMT showed no relationships. Conclusions: This study suggested that obesity in adolescence was related to an increase C-IMT in healthy young Korean men.
AB - Objectives: The aim of this study is to investigate the association between obesity indices (body mass index, weight, waist-hip ratio and waist circumference) in adolescents and the carotid intima-media thickness (C-IMT) in early adulthood. We also wanted to identify the best predictor for C-IMT among these obesity indices. Methods: This study used community-based prospective cohort study, known as the Kangwha Study, and the data we used were from subjects who were 16-years old in 1996 (defined as HadolescenceI) and 25 years-old in 2005 (defined as Hearly adulthoodI). The 256 subjects (113 men and 143 women) who were used for analysis participated in both follow-ups, and they underwent B-mode ultrasonography of the carotid arteries at the early adulthood follow-up. Obesity indices were defined as the body mass index, weight, waist-hip ratio and waist circumference. The C-IMT was defined as the mean of the maximal IMT of each common carotid artery. The C-IMT and obesity indices associations were evaluated via multivariable regression, logistic regression and the receiver-operator characteristic curve analyses. Results: In men, all the obesity indices in adolescence were showed to have statistically significant positive association with C-IMT in early adulthood. However, no such relationship was showed in women. On multiple regression and logistic regression analysis, the waist-hip ratio showed the biggest relationship with the C-IMT among the 4 obesity indices. However, there were no statistical significant differences and no best predictor was found. For the women, the obesity incidences and C-IMT showed no relationships. Conclusions: This study suggested that obesity in adolescence was related to an increase C-IMT in healthy young Korean men.
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UR - http://www.scopus.com/inward/citedby.url?scp=43249130719&partnerID=8YFLogxK
U2 - 10.3961/jpmph.2008.41.2.107
DO - 10.3961/jpmph.2008.41.2.107
M3 - Article
C2 - 18385551
AN - SCOPUS:43249130719
VL - 41
SP - 107
EP - 114
JO - Journal of Preventive Medicine and Public Health
JF - Journal of Preventive Medicine and Public Health
SN - 1975-8375
IS - 2
ER -