The association of visual impairment with clinical outcomes in hemodialysis patients

Yu Ah Hong, Suk Young Kim, Su Hyun Kim, Young Ok Kim, Dong Chan Jin, Ho Chul Song, Euy Jin Choi, Yong Lim Kim, Yon Su Kim, Shin Wook Kang, Nam Ho Kim, Chul Woo Yang, Yong Kyun Kim

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Visual impairment limits people's ability to perform daily tasks and affects their quality of life. We evaluated the impact of visual impairment on clinical outcomes in hemodialysis (HD) patients. HD patients were selected from the Clinical Research Center registry a prospective cohort study on dialysis patients in Korea. Visual impairment was defined as difficulty in daily life due to decreased visual acuity or blindness. The primary outcome was all-cause mortality and the secondary outcomes were cardiovascular and infection-related hospitalization. A total of 3250 patients were included. Seven hundred thirty (22.5%) of the enrolled patients had visual impairment. The median follow-up period was 30 months. The Kaplan-Meier curve and log-rank test showed that all-cause mortality rates (P<0.001) as well as cardiovascular and infection-related hospitalization rates (P<0.001 and P<0.001) were significantly higher in patients with visual impairment than in patients without visual impairment. In the multivariable analysis, visual impairment had significant predictive power for all-cause mortality (Hazard ratio [HR], 1.77, 95% confidence interval [CI], 1.21-2.61, P=0.004) and cardiovascular hospitalization (HR 1.45 [1.00-1.90], P=0.008) after adjusting for confounding variables. Of these 3250 patients, 634 patients from each group were matched by propensity scores. In the propensity score matched analysis, patients with visual impairment had independently significant associations with increased all-cause mortality (HR 1.69 [1.12-2.54], P=0.01) and cardiovascular hospitalization (HR 1.48 [1.08-2.02], P=0.01) compared with patients without visual impairment after adjustment for confounding variables. Our data demonstrated that visual impairment was an independent risk factor for clinical adverse outcomes in HD patients.

Original languageEnglish
Article numbere3591
JournalMedicine (United States)
Volume95
Issue number19
DOIs
Publication statusPublished - 2016 Jan 1

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Vision Disorders
Renal Dialysis
Hospitalization
Cardiovascular Infections
Propensity Score
Confounding Factors (Epidemiology)
Mortality
Aptitude
Blindness
Korea
Visual Acuity
Registries
Dialysis
Cohort Studies
Research Design
Quality of Life
Prospective Studies
Confidence Intervals

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Hong, Y. A., Kim, S. Y., Kim, S. H., Kim, Y. O., Jin, D. C., Song, H. C., ... Kim, Y. K. (2016). The association of visual impairment with clinical outcomes in hemodialysis patients. Medicine (United States), 95(19), [e3591]. https://doi.org/10.1097/MD.0000000000003591
Hong, Yu Ah ; Kim, Suk Young ; Kim, Su Hyun ; Kim, Young Ok ; Jin, Dong Chan ; Song, Ho Chul ; Choi, Euy Jin ; Kim, Yong Lim ; Kim, Yon Su ; Kang, Shin Wook ; Kim, Nam Ho ; Yang, Chul Woo ; Kim, Yong Kyun. / The association of visual impairment with clinical outcomes in hemodialysis patients. In: Medicine (United States). 2016 ; Vol. 95, No. 19.
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Hong, YA, Kim, SY, Kim, SH, Kim, YO, Jin, DC, Song, HC, Choi, EJ, Kim, YL, Kim, YS, Kang, SW, Kim, NH, Yang, CW & Kim, YK 2016, 'The association of visual impairment with clinical outcomes in hemodialysis patients', Medicine (United States), vol. 95, no. 19, e3591. https://doi.org/10.1097/MD.0000000000003591

The association of visual impairment with clinical outcomes in hemodialysis patients. / Hong, Yu Ah; Kim, Suk Young; Kim, Su Hyun; Kim, Young Ok; Jin, Dong Chan; Song, Ho Chul; Choi, Euy Jin; Kim, Yong Lim; Kim, Yon Su; Kang, Shin Wook; Kim, Nam Ho; Yang, Chul Woo; Kim, Yong Kyun.

In: Medicine (United States), Vol. 95, No. 19, e3591, 01.01.2016.

Research output: Contribution to journalArticle

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T1 - The association of visual impairment with clinical outcomes in hemodialysis patients

AU - Hong, Yu Ah

AU - Kim, Suk Young

AU - Kim, Su Hyun

AU - Kim, Young Ok

AU - Jin, Dong Chan

AU - Song, Ho Chul

AU - Choi, Euy Jin

AU - Kim, Yong Lim

AU - Kim, Yon Su

AU - Kang, Shin Wook

AU - Kim, Nam Ho

AU - Yang, Chul Woo

AU - Kim, Yong Kyun

PY - 2016/1/1

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N2 - Visual impairment limits people's ability to perform daily tasks and affects their quality of life. We evaluated the impact of visual impairment on clinical outcomes in hemodialysis (HD) patients. HD patients were selected from the Clinical Research Center registry a prospective cohort study on dialysis patients in Korea. Visual impairment was defined as difficulty in daily life due to decreased visual acuity or blindness. The primary outcome was all-cause mortality and the secondary outcomes were cardiovascular and infection-related hospitalization. A total of 3250 patients were included. Seven hundred thirty (22.5%) of the enrolled patients had visual impairment. The median follow-up period was 30 months. The Kaplan-Meier curve and log-rank test showed that all-cause mortality rates (P<0.001) as well as cardiovascular and infection-related hospitalization rates (P<0.001 and P<0.001) were significantly higher in patients with visual impairment than in patients without visual impairment. In the multivariable analysis, visual impairment had significant predictive power for all-cause mortality (Hazard ratio [HR], 1.77, 95% confidence interval [CI], 1.21-2.61, P=0.004) and cardiovascular hospitalization (HR 1.45 [1.00-1.90], P=0.008) after adjusting for confounding variables. Of these 3250 patients, 634 patients from each group were matched by propensity scores. In the propensity score matched analysis, patients with visual impairment had independently significant associations with increased all-cause mortality (HR 1.69 [1.12-2.54], P=0.01) and cardiovascular hospitalization (HR 1.48 [1.08-2.02], P=0.01) compared with patients without visual impairment after adjustment for confounding variables. Our data demonstrated that visual impairment was an independent risk factor for clinical adverse outcomes in HD patients.

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