The changes in prevalence and the related factors of Helicobacter pylori infection in Korean health check-up subjects during 8 years

Mi Young Do, Yongchan Lee, Chang Hwan Choi, Sang Joong Kim, Chang Sik Mun, Hong Ju Moon, Hyun Woong Lee, Hyung Chul Oh, Hyung Joon Kim, Jeong Wook Kim, Jae Hyuk Do, Jae Gyu Kim, Sae Kyung Chang

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Abstract

BACKGROUND/AIMS: The aim of this study was to evaluate the changes in prevalence and the related factors of Helicobacter pylori (H. pylori) infection in Korean health check-up subjects during the period of 8 years. METHODS: Among 89,231 subjects who visited the Health Promotion Centers of Severance hospital or Chung-Ang University hospital from Jan. 1998 through Dec. 2005, a total of 10,553 subjects who received esophagogastroduodenoscopy (EGD) and H. pylori test were enrolled. H. pylori infection was assessed by histologic examination. Changes of the prevalence of H. pylori infection during 8 years, and infection-related factors such as demographic characteristics, body mass index, ABO blood types, endoscopic findings (presence of peptic ulcer diseases), educational level, economic status, smoking habits, and alcohol intake in year 2005 were analyzed. RESULTS: The mean age of 10,553 subjects (7,329 men, 3,224 women) was 49.7+/-10.4 years (range from 17 to 92 years). The prevalence of H. pylori infection at the first, second, third, fourth, fifth, sixth, seventh, and eighth year were 64.7%, 58.1%, 54.2%, 50.4%, 48.9%, 49.5%, 39.6%, and 40.0%, respectively, and these serial decreases in prevalence over 8 years were statistically significant (p<0.001). Regardless of sex, age or EGD findings, the prevalence of H. pylori infection was significantly decreased. In the analysis of the H. pylori infection-related factors in 2005, only age and EGD findings (peptic ulcer diseases) were significant factors. CONCLUSIONS: The prevalence of H. pylori infection was significantly decreased during 8-year period in Korean health check-up subjects. Age and peptic ulcer diseases were the two significant factors related to H. pylori infection in Korea.

Original languageEnglish
Pages (from-to)76-83
Number of pages8
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume53
Issue number2
Publication statusPublished - 2009 Jan 1

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Helicobacter Infections
Helicobacter pylori
Health
Digestive System Endoscopy
Peptic Ulcer
Korea
Health Promotion
Habits
Body Mass Index
Smoking
Alcohols
Economics
Demography
Infection

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Do, Mi Young ; Lee, Yongchan ; Choi, Chang Hwan ; Kim, Sang Joong ; Mun, Chang Sik ; Moon, Hong Ju ; Lee, Hyun Woong ; Oh, Hyung Chul ; Kim, Hyung Joon ; Kim, Jeong Wook ; Do, Jae Hyuk ; Kim, Jae Gyu ; Chang, Sae Kyung. / The changes in prevalence and the related factors of Helicobacter pylori infection in Korean health check-up subjects during 8 years. In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi. 2009 ; Vol. 53, No. 2. pp. 76-83.
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title = "The changes in prevalence and the related factors of Helicobacter pylori infection in Korean health check-up subjects during 8 years",
abstract = "BACKGROUND/AIMS: The aim of this study was to evaluate the changes in prevalence and the related factors of Helicobacter pylori (H. pylori) infection in Korean health check-up subjects during the period of 8 years. METHODS: Among 89,231 subjects who visited the Health Promotion Centers of Severance hospital or Chung-Ang University hospital from Jan. 1998 through Dec. 2005, a total of 10,553 subjects who received esophagogastroduodenoscopy (EGD) and H. pylori test were enrolled. H. pylori infection was assessed by histologic examination. Changes of the prevalence of H. pylori infection during 8 years, and infection-related factors such as demographic characteristics, body mass index, ABO blood types, endoscopic findings (presence of peptic ulcer diseases), educational level, economic status, smoking habits, and alcohol intake in year 2005 were analyzed. RESULTS: The mean age of 10,553 subjects (7,329 men, 3,224 women) was 49.7+/-10.4 years (range from 17 to 92 years). The prevalence of H. pylori infection at the first, second, third, fourth, fifth, sixth, seventh, and eighth year were 64.7{\%}, 58.1{\%}, 54.2{\%}, 50.4{\%}, 48.9{\%}, 49.5{\%}, 39.6{\%}, and 40.0{\%}, respectively, and these serial decreases in prevalence over 8 years were statistically significant (p<0.001). Regardless of sex, age or EGD findings, the prevalence of H. pylori infection was significantly decreased. In the analysis of the H. pylori infection-related factors in 2005, only age and EGD findings (peptic ulcer diseases) were significant factors. CONCLUSIONS: The prevalence of H. pylori infection was significantly decreased during 8-year period in Korean health check-up subjects. Age and peptic ulcer diseases were the two significant factors related to H. pylori infection in Korea.",
author = "Do, {Mi Young} and Yongchan Lee and Choi, {Chang Hwan} and Kim, {Sang Joong} and Mun, {Chang Sik} and Moon, {Hong Ju} and Lee, {Hyun Woong} and Oh, {Hyung Chul} and Kim, {Hyung Joon} and Kim, {Jeong Wook} and Do, {Jae Hyuk} and Kim, {Jae Gyu} and Chang, {Sae Kyung}",
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Do, MY, Lee, Y, Choi, CH, Kim, SJ, Mun, CS, Moon, HJ, Lee, HW, Oh, HC, Kim, HJ, Kim, JW, Do, JH, Kim, JG & Chang, SK 2009, 'The changes in prevalence and the related factors of Helicobacter pylori infection in Korean health check-up subjects during 8 years', The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, vol. 53, no. 2, pp. 76-83.

The changes in prevalence and the related factors of Helicobacter pylori infection in Korean health check-up subjects during 8 years. / Do, Mi Young; Lee, Yongchan; Choi, Chang Hwan; Kim, Sang Joong; Mun, Chang Sik; Moon, Hong Ju; Lee, Hyun Woong; Oh, Hyung Chul; Kim, Hyung Joon; Kim, Jeong Wook; Do, Jae Hyuk; Kim, Jae Gyu; Chang, Sae Kyung.

In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 53, No. 2, 01.01.2009, p. 76-83.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The changes in prevalence and the related factors of Helicobacter pylori infection in Korean health check-up subjects during 8 years

AU - Do, Mi Young

AU - Lee, Yongchan

AU - Choi, Chang Hwan

AU - Kim, Sang Joong

AU - Mun, Chang Sik

AU - Moon, Hong Ju

AU - Lee, Hyun Woong

AU - Oh, Hyung Chul

AU - Kim, Hyung Joon

AU - Kim, Jeong Wook

AU - Do, Jae Hyuk

AU - Kim, Jae Gyu

AU - Chang, Sae Kyung

PY - 2009/1/1

Y1 - 2009/1/1

N2 - BACKGROUND/AIMS: The aim of this study was to evaluate the changes in prevalence and the related factors of Helicobacter pylori (H. pylori) infection in Korean health check-up subjects during the period of 8 years. METHODS: Among 89,231 subjects who visited the Health Promotion Centers of Severance hospital or Chung-Ang University hospital from Jan. 1998 through Dec. 2005, a total of 10,553 subjects who received esophagogastroduodenoscopy (EGD) and H. pylori test were enrolled. H. pylori infection was assessed by histologic examination. Changes of the prevalence of H. pylori infection during 8 years, and infection-related factors such as demographic characteristics, body mass index, ABO blood types, endoscopic findings (presence of peptic ulcer diseases), educational level, economic status, smoking habits, and alcohol intake in year 2005 were analyzed. RESULTS: The mean age of 10,553 subjects (7,329 men, 3,224 women) was 49.7+/-10.4 years (range from 17 to 92 years). The prevalence of H. pylori infection at the first, second, third, fourth, fifth, sixth, seventh, and eighth year were 64.7%, 58.1%, 54.2%, 50.4%, 48.9%, 49.5%, 39.6%, and 40.0%, respectively, and these serial decreases in prevalence over 8 years were statistically significant (p<0.001). Regardless of sex, age or EGD findings, the prevalence of H. pylori infection was significantly decreased. In the analysis of the H. pylori infection-related factors in 2005, only age and EGD findings (peptic ulcer diseases) were significant factors. CONCLUSIONS: The prevalence of H. pylori infection was significantly decreased during 8-year period in Korean health check-up subjects. Age and peptic ulcer diseases were the two significant factors related to H. pylori infection in Korea.

AB - BACKGROUND/AIMS: The aim of this study was to evaluate the changes in prevalence and the related factors of Helicobacter pylori (H. pylori) infection in Korean health check-up subjects during the period of 8 years. METHODS: Among 89,231 subjects who visited the Health Promotion Centers of Severance hospital or Chung-Ang University hospital from Jan. 1998 through Dec. 2005, a total of 10,553 subjects who received esophagogastroduodenoscopy (EGD) and H. pylori test were enrolled. H. pylori infection was assessed by histologic examination. Changes of the prevalence of H. pylori infection during 8 years, and infection-related factors such as demographic characteristics, body mass index, ABO blood types, endoscopic findings (presence of peptic ulcer diseases), educational level, economic status, smoking habits, and alcohol intake in year 2005 were analyzed. RESULTS: The mean age of 10,553 subjects (7,329 men, 3,224 women) was 49.7+/-10.4 years (range from 17 to 92 years). The prevalence of H. pylori infection at the first, second, third, fourth, fifth, sixth, seventh, and eighth year were 64.7%, 58.1%, 54.2%, 50.4%, 48.9%, 49.5%, 39.6%, and 40.0%, respectively, and these serial decreases in prevalence over 8 years were statistically significant (p<0.001). Regardless of sex, age or EGD findings, the prevalence of H. pylori infection was significantly decreased. In the analysis of the H. pylori infection-related factors in 2005, only age and EGD findings (peptic ulcer diseases) were significant factors. CONCLUSIONS: The prevalence of H. pylori infection was significantly decreased during 8-year period in Korean health check-up subjects. Age and peptic ulcer diseases were the two significant factors related to H. pylori infection in Korea.

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M3 - Article

VL - 53

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JO - The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi

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