Four new compounds (1–3 and 5), along with 17 known compounds, were isolated from the twigs of Lindera glauca (Siebold & Zucc.) Blume. The absolute configuration of compound 4 was determined for the first time in the present study. The structures of compounds were determined on the basis of extensive spectroscopic methods, including 1D and 2D NMR and CD spectroscopic data. All isolated compounds were tested for their antiviral activities against HRV1B-, CVB3-, and PR8-infected Vero cells. Among the tested compounds, (+)-9′-O-trans-feruloyl-5,5′-dimethoxylariciresinol exhibited the most consistent and effective antiviral activities on both HRV1B and CVB3 infected cells.
Bibliographical noteFunding Information:
This research was supported by the National Research Foundation of Korea (NRF) grant [ NRF-2016R1A2B4006742 and NRF-2017R1A6A3A11029000 ] funded by the Ministry of Education, Science and Technology , Republic of Korea, and the Basic Science Research Program for Young Researchers funded by the Richwood Pharmaceutical Company , Republic of Korea.
All Science Journal Classification (ASJC) codes
- Agronomy and Crop Science
- Plant Science