The importance of vegetables as an allergen for the development of hand eczema has been a matter of debate. The aim of this study was to evaluate the clinical manifestations of hand eczema and to investigate the role of vegetables in the hand eczema of Korean housewives. In this study, clinical evaluations and patch tests with Hollister-Stier standard allergens and 22 vegetable allergens were performed in 32 patients with housewife's hand eczema. The results are summarized as follows: 1. The prevalence was highest in fourth (59.4%) and third (25.0%) decades of life and the peak age of onset was third (53.1%) and fourth (31.3%) decades. 2. Only 3 of 32 patients (9.4%) had past histories of atopic dermatitis; however, children of 12 patients (37.5%) had atopic dermatitis. 3. The common skin signs were fissuring (90.6%), scaling (78.1%), erythema (75.0%), hyperkeratosis (71.9%), lichenification (62.5%) and vesicle (43.8%) in descending order. 4. The common aggravating factors were soap or detergent (93.8%), water (90.6%) and rubber glove ( 25.0%). 5. The most common involved areas of hand eczema were fingers including fingertips and fingertips only. 6. The results of patch test using vegetable allergens with 10 normal controls were all negative. Of the 32 patients with hand eczema, 12 (37.5%) showed positive patch test with standard allergens and 5 (15.6%) were positive with vegetable allergens. 7. Among 30 standard allergens, cinnamic alcohol (9.4%), potassium dichromate (9.4%), nickel sulfate (6.3%), and wool wax alcohol (6.3%) were the common allergens which showed positive reactions. Of the 22 vegetable allergens, garlic, Chinese cabbage juice, Chinese cabbage extract, cucumber juice, spinach extract, potato juice showed weak positive reactions in only one patient (3.1%) respectively. From the above results we concluded that contact sensitivity to vegetables is not significant in Korean housewives with hand eczema.
|Number of pages||7|
|Journal||Korean Journal of Dermatology|
|Publication status||Published - 1988 Jan 1|
All Science Journal Classification (ASJC) codes