The clinical significance of a positive Amnisure test™ in women with term labor with intact membranes

Seung Mi Lee, Joonho Lee, Hyo Suk Seong, Si Eun Lee, Joong Shin Park, Roberto Romero, Bo Hyun Yoon

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Objective.The Amnisure ROM™ test is approved for the diagnosis of rupture of membranes ROM. Yet, a fraction of patients with a positive test have intact membranes by sterile speculum examination. The objective of this study was to determine the clinical significance of this finding. Methods.The study population consisted of four groups of nulliparous women at term: 1 not in labor without clinical evidence of ROM n 125; 2 in labor without clinical ROM with a negative Amnisure test™ n 56; 3 in labor without clinical ROM with a positive Amnisure test™ n 25; and 4 in labor with clinical ROM n 30. The Amnisure test™ was performed in cases without clinical ROM Groups 1, 2 and 3. Results.1 The Amnisure test™ was positive more frequently in women in labor with intact membranes than in patients not in labor at term without ROM 30.9 2581 women vs. 4.8 6125 women; p < 0.001; 2 patients in labor without clinical ROM with a positive Amnisure test™ had a significantly shorter admission-to-delivery interval than those in labor without clinical ROM with a negative Amnisure test™ p < 0.05. Conclusion.1 A positive Amnisure test™ is present in about one-third nulliparous women at term presenting in labor with intact membranes; 2 patients with a positive Amnisure test™ had a shorter admission-to-delivery interval than those with a negative test.

Original languageEnglish
Pages (from-to)305-310
Number of pages6
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume22
Issue number4
DOIs
Publication statusPublished - 2009 Nov 6

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Membranes
Surgical Instruments
Rupture
Population

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

Cite this

Lee, Seung Mi ; Lee, Joonho ; Seong, Hyo Suk ; Lee, Si Eun ; Park, Joong Shin ; Romero, Roberto ; Yoon, Bo Hyun. / The clinical significance of a positive Amnisure test™ in women with term labor with intact membranes. In: Journal of Maternal-Fetal and Neonatal Medicine. 2009 ; Vol. 22, No. 4. pp. 305-310.
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abstract = "Objective.The Amnisure ROM™ test is approved for the diagnosis of rupture of membranes ROM. Yet, a fraction of patients with a positive test have intact membranes by sterile speculum examination. The objective of this study was to determine the clinical significance of this finding. Methods.The study population consisted of four groups of nulliparous women at term: 1 not in labor without clinical evidence of ROM n 125; 2 in labor without clinical ROM with a negative Amnisure test™ n 56; 3 in labor without clinical ROM with a positive Amnisure test™ n 25; and 4 in labor with clinical ROM n 30. The Amnisure test™ was performed in cases without clinical ROM Groups 1, 2 and 3. Results.1 The Amnisure test™ was positive more frequently in women in labor with intact membranes than in patients not in labor at term without ROM 30.9 2581 women vs. 4.8 6125 women; p < 0.001; 2 patients in labor without clinical ROM with a positive Amnisure test™ had a significantly shorter admission-to-delivery interval than those in labor without clinical ROM with a negative Amnisure test™ p < 0.05. Conclusion.1 A positive Amnisure test™ is present in about one-third nulliparous women at term presenting in labor with intact membranes; 2 patients with a positive Amnisure test™ had a shorter admission-to-delivery interval than those with a negative test.",
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The clinical significance of a positive Amnisure test™ in women with term labor with intact membranes. / Lee, Seung Mi; Lee, Joonho; Seong, Hyo Suk; Lee, Si Eun; Park, Joong Shin; Romero, Roberto; Yoon, Bo Hyun.

In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 22, No. 4, 06.11.2009, p. 305-310.

Research output: Contribution to journalArticle

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AU - Romero, Roberto

AU - Yoon, Bo Hyun

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N2 - Objective.The Amnisure ROM™ test is approved for the diagnosis of rupture of membranes ROM. Yet, a fraction of patients with a positive test have intact membranes by sterile speculum examination. The objective of this study was to determine the clinical significance of this finding. Methods.The study population consisted of four groups of nulliparous women at term: 1 not in labor without clinical evidence of ROM n 125; 2 in labor without clinical ROM with a negative Amnisure test™ n 56; 3 in labor without clinical ROM with a positive Amnisure test™ n 25; and 4 in labor with clinical ROM n 30. The Amnisure test™ was performed in cases without clinical ROM Groups 1, 2 and 3. Results.1 The Amnisure test™ was positive more frequently in women in labor with intact membranes than in patients not in labor at term without ROM 30.9 2581 women vs. 4.8 6125 women; p < 0.001; 2 patients in labor without clinical ROM with a positive Amnisure test™ had a significantly shorter admission-to-delivery interval than those in labor without clinical ROM with a negative Amnisure test™ p < 0.05. Conclusion.1 A positive Amnisure test™ is present in about one-third nulliparous women at term presenting in labor with intact membranes; 2 patients with a positive Amnisure test™ had a shorter admission-to-delivery interval than those with a negative test.

AB - Objective.The Amnisure ROM™ test is approved for the diagnosis of rupture of membranes ROM. Yet, a fraction of patients with a positive test have intact membranes by sterile speculum examination. The objective of this study was to determine the clinical significance of this finding. Methods.The study population consisted of four groups of nulliparous women at term: 1 not in labor without clinical evidence of ROM n 125; 2 in labor without clinical ROM with a negative Amnisure test™ n 56; 3 in labor without clinical ROM with a positive Amnisure test™ n 25; and 4 in labor with clinical ROM n 30. The Amnisure test™ was performed in cases without clinical ROM Groups 1, 2 and 3. Results.1 The Amnisure test™ was positive more frequently in women in labor with intact membranes than in patients not in labor at term without ROM 30.9 2581 women vs. 4.8 6125 women; p < 0.001; 2 patients in labor without clinical ROM with a positive Amnisure test™ had a significantly shorter admission-to-delivery interval than those in labor without clinical ROM with a negative Amnisure test™ p < 0.05. Conclusion.1 A positive Amnisure test™ is present in about one-third nulliparous women at term presenting in labor with intact membranes; 2 patients with a positive Amnisure test™ had a shorter admission-to-delivery interval than those with a negative test.

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