The development of irritable bowel syndrome after Shigella infection

3 year follow-up study

Hee Sun Kim, Min Su Kim, Sang Won Ji, HyoJin Park

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

BACKGROUND/AIMS: Bacterial gastroenteritis seems to be a risk factor of irritable bowel syndrome (IBS). The incidence of post-infectious IBS (PI-IBS) was reported to be in the range of 7-31%, but few studies have reported long term follow-up results. So, we investigated the clinical course and prognosis of PI-IBS three years after shigella infection. METHODS: The subjects were recruited from our previous study, in which we investigated the incidence and risk factors of PI-IBS. We had a questionnaire based on interview with 120 controls and 124 patients who had shigella infection three years ago. Both groups were evaluated for the presence of IBS, functional bowel disorders (FBD) except IBS before, one and three years after the infection, respectively. RESULTS: Ninety-five patients (76.6%) and 105 controls (87.5%) completed the questionnaire. In patients group, 7 cases had IBS prior to infection (previous IBS), 12 cases (13.8%) had IBS after 1 year (PI-IBS). Four cases developed IBS newly after 3 years (new IBS). Thirteen cases (14.9%) in patients and 4 cases (4.5%) in controls had IBS over 3 years (OR 3.93: 1.20-12.86). The recovery rate over 3 years were 50.0% (2/4) in previous IBS and 25% (3/12) in PI-IBS. The incidence of PI-IBS after 3 years in previous FBD subjects was 28.6% and was 10.6% in normals (p<0.05). The female gender was a risk factor for FBD. CONCLUSIONS: Bacterial gastroenteritis is a trigger factor of IBS. About a quarter of PI-IBS patients are recovered over 3 years. Previous FBD except IBS is a risk factor after 3 years.

Original languageEnglish
Pages (from-to)300-305
Number of pages6
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume47
Issue number4
Publication statusPublished - 2006 Jan 1

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Shigella
Irritable Bowel Syndrome
Infection
Gastroenteritis
Incidence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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title = "The development of irritable bowel syndrome after Shigella infection: 3 year follow-up study",
abstract = "BACKGROUND/AIMS: Bacterial gastroenteritis seems to be a risk factor of irritable bowel syndrome (IBS). The incidence of post-infectious IBS (PI-IBS) was reported to be in the range of 7-31{\%}, but few studies have reported long term follow-up results. So, we investigated the clinical course and prognosis of PI-IBS three years after shigella infection. METHODS: The subjects were recruited from our previous study, in which we investigated the incidence and risk factors of PI-IBS. We had a questionnaire based on interview with 120 controls and 124 patients who had shigella infection three years ago. Both groups were evaluated for the presence of IBS, functional bowel disorders (FBD) except IBS before, one and three years after the infection, respectively. RESULTS: Ninety-five patients (76.6{\%}) and 105 controls (87.5{\%}) completed the questionnaire. In patients group, 7 cases had IBS prior to infection (previous IBS), 12 cases (13.8{\%}) had IBS after 1 year (PI-IBS). Four cases developed IBS newly after 3 years (new IBS). Thirteen cases (14.9{\%}) in patients and 4 cases (4.5{\%}) in controls had IBS over 3 years (OR 3.93: 1.20-12.86). The recovery rate over 3 years were 50.0{\%} (2/4) in previous IBS and 25{\%} (3/12) in PI-IBS. The incidence of PI-IBS after 3 years in previous FBD subjects was 28.6{\%} and was 10.6{\%} in normals (p<0.05). The female gender was a risk factor for FBD. CONCLUSIONS: Bacterial gastroenteritis is a trigger factor of IBS. About a quarter of PI-IBS patients are recovered over 3 years. Previous FBD except IBS is a risk factor after 3 years.",
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The development of irritable bowel syndrome after Shigella infection : 3 year follow-up study. / Kim, Hee Sun; Kim, Min Su; Ji, Sang Won; Park, HyoJin.

In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 47, No. 4, 01.01.2006, p. 300-305.

Research output: Contribution to journalArticle

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