The effect of lif-maleic acid added calcium aluminate bone cement and Ca-Pmma composite bone cement on bone regeneration in rat calvarial defects

Ui-Won Jung, J. A. Shin, K. J. Chae, Y. K. Lee, C. K. Kim, Seongho Choi

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Abstract

The purpose of this study was to evaluate histologically the effect of LiF-maleic acid added calcium aluminate (LM-CA) bone cement and calcium aluminate-polymethylmethacrylate (CA-PMMA) composite bone cement on bone regeneration in rat calvarial defect. After calvarial defects in 8 mm in diameter were created, three groups of 10 animals, a total of 30, each either received LM-CA bone cement, CA-PMMA composite bone cement or a sham-surgery control. Histologic analysis was done at 2 weeks and 8 weeks of healing periods. We concluded that LM-CA bone cement can be used as a bioactive bone graft material due to ability of bonding to the existing bone and CA-PMMA can be used as a graft material for augmentation of bone-volume due to dimensional stability.

Original languageEnglish
Pages (from-to)851-854
Number of pages4
JournalKey Engineering Materials
Volume330-332 II
Publication statusPublished - 2007 Jan 24

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All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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