The effect of specialized continuous renal replacement therapy team in acute kidney injury patients treatment

Youn Kyung Kee, Eun Jin Kim, Kyoung Sook Park, Seung Gyu Han, In Mee Han, Chang Yun Yoon, Eunyoung Lee, Young Su Joo, Dae Young Kim, Mi Jung Lee, Jung Tak Park, SeungHyeok Han, TaeHyun Yoo, Beom Seok Kim, Shin-Wook Kang, Kyu Hun Choi, Hyung Jung Oh

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Purpose: Continuous renal replacement therapy (CRRT) has been established for critically ill acute kidney injury (AKI) patients. In addition, some centers consist of a specialized CRRT team (SCT) with physicians and nurses. To our best knowledge, however, ona a few studies have yet been carried out on the superiority of SCT management. Materials and Methods: A total of 551 patients, who received CRRT between January 2008 and March 2009, were divided into two groups based on the controller of CRRT. The impact of the CRRT management on 28-day mortality was compared between two groups by Kaplan-Meier curve and Cox analysis. Results: During the study period, the number of filters used, down-time per day, and intensive care unit length of day were significantly higher in non-SCT group than in SCT group (6.2 hrs vs. 5.0 hrs, p=0.042; 5.0 hrs vs. 3.8 hrs, p<0.001; 27.5 days vs. 21.1 days, p=0.027, respectively), while net ultrafiltration rate was significantly lower in non-SCT group than SCT group (28.0 mL/kg/hr vs. 29.5 mL/kg/hr, p=0.043, respectively). In addition, 28-day mortality rate was significantly lower in SCT group than with non-SCT group (p=0.031). Moreover, Cox regression analysis showed that 28-day mortality rate was significantly lower in SCT control group, even after adjusting for age, gender, severity scores, biomarkers, risk, injury, failure, loss, and end-stage renal disease, and contributing factors (hazard ratio 0.91, p=0.046). Conclusion: A well-trained CRRT team could be beneficial for mortality improvement of AKI patients requiring CRRT.

Original languageEnglish
Pages (from-to)658-665
Number of pages8
JournalYonsei medical journal
Volume56
Issue number3
DOIs
Publication statusPublished - 2015 Jan 1

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Renal Replacement Therapy
Acute Kidney Injury
Mortality
Therapeutics
Ultrafiltration
Critical Illness
Chronic Kidney Failure
Intensive Care Units
Biomarkers
Nurses
Regression Analysis
Physicians
Control Groups
Wounds and Injuries

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kee, Y. K., Kim, E. J., Park, K. S., Han, S. G., Han, I. M., Yoon, C. Y., ... Oh, H. J. (2015). The effect of specialized continuous renal replacement therapy team in acute kidney injury patients treatment. Yonsei medical journal, 56(3), 658-665. https://doi.org/10.3349/ymj.2015.56.3.658
Kee, Youn Kyung ; Kim, Eun Jin ; Park, Kyoung Sook ; Han, Seung Gyu ; Han, In Mee ; Yoon, Chang Yun ; Lee, Eunyoung ; Joo, Young Su ; Kim, Dae Young ; Lee, Mi Jung ; Park, Jung Tak ; Han, SeungHyeok ; Yoo, TaeHyun ; Kim, Beom Seok ; Kang, Shin-Wook ; Choi, Kyu Hun ; Oh, Hyung Jung. / The effect of specialized continuous renal replacement therapy team in acute kidney injury patients treatment. In: Yonsei medical journal. 2015 ; Vol. 56, No. 3. pp. 658-665.
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abstract = "Purpose: Continuous renal replacement therapy (CRRT) has been established for critically ill acute kidney injury (AKI) patients. In addition, some centers consist of a specialized CRRT team (SCT) with physicians and nurses. To our best knowledge, however, ona a few studies have yet been carried out on the superiority of SCT management. Materials and Methods: A total of 551 patients, who received CRRT between January 2008 and March 2009, were divided into two groups based on the controller of CRRT. The impact of the CRRT management on 28-day mortality was compared between two groups by Kaplan-Meier curve and Cox analysis. Results: During the study period, the number of filters used, down-time per day, and intensive care unit length of day were significantly higher in non-SCT group than in SCT group (6.2 hrs vs. 5.0 hrs, p=0.042; 5.0 hrs vs. 3.8 hrs, p<0.001; 27.5 days vs. 21.1 days, p=0.027, respectively), while net ultrafiltration rate was significantly lower in non-SCT group than SCT group (28.0 mL/kg/hr vs. 29.5 mL/kg/hr, p=0.043, respectively). In addition, 28-day mortality rate was significantly lower in SCT group than with non-SCT group (p=0.031). Moreover, Cox regression analysis showed that 28-day mortality rate was significantly lower in SCT control group, even after adjusting for age, gender, severity scores, biomarkers, risk, injury, failure, loss, and end-stage renal disease, and contributing factors (hazard ratio 0.91, p=0.046). Conclusion: A well-trained CRRT team could be beneficial for mortality improvement of AKI patients requiring CRRT.",
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Kee, YK, Kim, EJ, Park, KS, Han, SG, Han, IM, Yoon, CY, Lee, E, Joo, YS, Kim, DY, Lee, MJ, Park, JT, Han, S, Yoo, T, Kim, BS, Kang, S-W, Choi, KH & Oh, HJ 2015, 'The effect of specialized continuous renal replacement therapy team in acute kidney injury patients treatment', Yonsei medical journal, vol. 56, no. 3, pp. 658-665. https://doi.org/10.3349/ymj.2015.56.3.658

The effect of specialized continuous renal replacement therapy team in acute kidney injury patients treatment. / Kee, Youn Kyung; Kim, Eun Jin; Park, Kyoung Sook; Han, Seung Gyu; Han, In Mee; Yoon, Chang Yun; Lee, Eunyoung; Joo, Young Su; Kim, Dae Young; Lee, Mi Jung; Park, Jung Tak; Han, SeungHyeok; Yoo, TaeHyun; Kim, Beom Seok; Kang, Shin-Wook; Choi, Kyu Hun; Oh, Hyung Jung.

In: Yonsei medical journal, Vol. 56, No. 3, 01.01.2015, p. 658-665.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The effect of specialized continuous renal replacement therapy team in acute kidney injury patients treatment

AU - Kee, Youn Kyung

AU - Kim, Eun Jin

AU - Park, Kyoung Sook

AU - Han, Seung Gyu

AU - Han, In Mee

AU - Yoon, Chang Yun

AU - Lee, Eunyoung

AU - Joo, Young Su

AU - Kim, Dae Young

AU - Lee, Mi Jung

AU - Park, Jung Tak

AU - Han, SeungHyeok

AU - Yoo, TaeHyun

AU - Kim, Beom Seok

AU - Kang, Shin-Wook

AU - Choi, Kyu Hun

AU - Oh, Hyung Jung

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Purpose: Continuous renal replacement therapy (CRRT) has been established for critically ill acute kidney injury (AKI) patients. In addition, some centers consist of a specialized CRRT team (SCT) with physicians and nurses. To our best knowledge, however, ona a few studies have yet been carried out on the superiority of SCT management. Materials and Methods: A total of 551 patients, who received CRRT between January 2008 and March 2009, were divided into two groups based on the controller of CRRT. The impact of the CRRT management on 28-day mortality was compared between two groups by Kaplan-Meier curve and Cox analysis. Results: During the study period, the number of filters used, down-time per day, and intensive care unit length of day were significantly higher in non-SCT group than in SCT group (6.2 hrs vs. 5.0 hrs, p=0.042; 5.0 hrs vs. 3.8 hrs, p<0.001; 27.5 days vs. 21.1 days, p=0.027, respectively), while net ultrafiltration rate was significantly lower in non-SCT group than SCT group (28.0 mL/kg/hr vs. 29.5 mL/kg/hr, p=0.043, respectively). In addition, 28-day mortality rate was significantly lower in SCT group than with non-SCT group (p=0.031). Moreover, Cox regression analysis showed that 28-day mortality rate was significantly lower in SCT control group, even after adjusting for age, gender, severity scores, biomarkers, risk, injury, failure, loss, and end-stage renal disease, and contributing factors (hazard ratio 0.91, p=0.046). Conclusion: A well-trained CRRT team could be beneficial for mortality improvement of AKI patients requiring CRRT.

AB - Purpose: Continuous renal replacement therapy (CRRT) has been established for critically ill acute kidney injury (AKI) patients. In addition, some centers consist of a specialized CRRT team (SCT) with physicians and nurses. To our best knowledge, however, ona a few studies have yet been carried out on the superiority of SCT management. Materials and Methods: A total of 551 patients, who received CRRT between January 2008 and March 2009, were divided into two groups based on the controller of CRRT. The impact of the CRRT management on 28-day mortality was compared between two groups by Kaplan-Meier curve and Cox analysis. Results: During the study period, the number of filters used, down-time per day, and intensive care unit length of day were significantly higher in non-SCT group than in SCT group (6.2 hrs vs. 5.0 hrs, p=0.042; 5.0 hrs vs. 3.8 hrs, p<0.001; 27.5 days vs. 21.1 days, p=0.027, respectively), while net ultrafiltration rate was significantly lower in non-SCT group than SCT group (28.0 mL/kg/hr vs. 29.5 mL/kg/hr, p=0.043, respectively). In addition, 28-day mortality rate was significantly lower in SCT group than with non-SCT group (p=0.031). Moreover, Cox regression analysis showed that 28-day mortality rate was significantly lower in SCT control group, even after adjusting for age, gender, severity scores, biomarkers, risk, injury, failure, loss, and end-stage renal disease, and contributing factors (hazard ratio 0.91, p=0.046). Conclusion: A well-trained CRRT team could be beneficial for mortality improvement of AKI patients requiring CRRT.

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