The effects of calcium aluminate cement according to particle sizes on calvarial bone defects in rats

J. A. Shin, S. U. Im, S. E. Song, C. S. Kim, S. Y. Choi, Y. K. Lee, K. N. Kim, C. K. Kim, S. H. Choi

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Abstract

This present study was carried out to find out the effects of calcium aluminate cement(CaO-Al203, CAC), which has been developed with biocompatibility and mechanical properties, in biological environments. Two different particle sizes of CAC - 3.5 μm vs. 212-250 μm which is recommended in periodontal bone grafting procedures - were filled in 8mm calvarial defects in Sprague-Dawley rats. The specimens were examined histologically, especially the bone-cement interface and the response of surrounding tissues. The result of this study shows that when calvarial defects in white rats are filled with 212-250 μm calcium aluminate cement, the materials proved to be bio-compatible in growth and healing on the surrounding tissues. When further researches on direct bone adhesion and bone regeneration ability are fulfilled, CAC is expected to be applied to various fields of periodontology in the future.

Original languageEnglish
Pages (from-to)113-116
Number of pages4
JournalKey Engineering Materials
Volume284-286
Publication statusPublished - 2005 Dec 1

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All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Shin, J. A., Im, S. U., Song, S. E., Kim, C. S., Choi, S. Y., Lee, Y. K., Kim, K. N., Kim, C. K., & Choi, S. H. (2005). The effects of calcium aluminate cement according to particle sizes on calvarial bone defects in rats. Key Engineering Materials, 284-286, 113-116.