Abstract
Background and Objectives: Supervised lifestyle interventions, including dietary and exercise programs, may be infeasible to implement in real-world settings. Therefore, this study aimed to evaluate the effectiveness of a home-based lifestyle modification intervention on blood pressure (BP) management. Methods: Eighty-five patients aged over 20 years and diagnosed with prehypertension or mild hypertension were randomly assigned to an advice-only comparison group (C group, n=28), a Dietary Approaches to Stop Hypertension (DASH) diet education group (D group, n=30), or a DASH and home-based exercise group (D+Ex group, n=27). The intervention lasted for 8 weeks. The primary outcome was the difference in office systolic blood pressure (SBP) before and after the study period (Trial registry at ClinicalTrials.gov, NCT01637909). Results: Seventy-two participants (87.8%) completed the trial. The degree of change in office SBP did not significantly differ among the intervention groups; however, the D+Ex group demonstrated a tendency toward decreased SBP. Upon analysis of 24-hour ambulatory BP measurements, daytime ambulatory SBP was significantly lower in the D+Ex group (134 mmHg; 95% confidence interval [CI], 131 to 137; p=0.011) than in the C group (139.5 mmHg; 95% CI, 130.9 to 137), and daytime ambulatory SBP was significantly decreased in the D+Ex group (?5.2 mmHg; 95% CI, ?8.3 to ?2.1; p=0.011) compared to the C group (0.4 mmHg, 95% CI, ?2.5 to 3.3). Conclusions: In conclusion, lifestyle modification emphasizing both diet and exercise was effective for lowering BP and should be favored over diet-only modifications.
| Original language | English |
|---|---|
| Pages (from-to) | 637-651 |
| Number of pages | 15 |
| Journal | Korean Circulation Journal |
| Volume | 48 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2018 Jul |
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All Science Journal Classification (ASJC) codes
- Internal Medicine
- Cardiology and Cardiovascular Medicine
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The effects of diet alone or in combination with exercise in patients with prehypertension and hypertension : A randomized controlled trial. / Lee, Chan Joo; Kim, Ji Young; Shim, Eugene; Hong, Sung Hyun; Lee, Mi Kyung; Jeon, Justin Y.; Park, Sungha.
In: Korean Circulation Journal, Vol. 48, No. 7, 07.2018, p. 637-651.Research output: Contribution to journal › Article
TY - JOUR
T1 - The effects of diet alone or in combination with exercise in patients with prehypertension and hypertension
T2 - A randomized controlled trial
AU - Lee, Chan Joo
AU - Kim, Ji Young
AU - Shim, Eugene
AU - Hong, Sung Hyun
AU - Lee, Mi Kyung
AU - Jeon, Justin Y.
AU - Park, Sungha
PY - 2018/7
Y1 - 2018/7
N2 - Background and Objectives: Supervised lifestyle interventions, including dietary and exercise programs, may be infeasible to implement in real-world settings. Therefore, this study aimed to evaluate the effectiveness of a home-based lifestyle modification intervention on blood pressure (BP) management. Methods: Eighty-five patients aged over 20 years and diagnosed with prehypertension or mild hypertension were randomly assigned to an advice-only comparison group (C group, n=28), a Dietary Approaches to Stop Hypertension (DASH) diet education group (D group, n=30), or a DASH and home-based exercise group (D+Ex group, n=27). The intervention lasted for 8 weeks. The primary outcome was the difference in office systolic blood pressure (SBP) before and after the study period (Trial registry at ClinicalTrials.gov, NCT01637909). Results: Seventy-two participants (87.8%) completed the trial. The degree of change in office SBP did not significantly differ among the intervention groups; however, the D+Ex group demonstrated a tendency toward decreased SBP. Upon analysis of 24-hour ambulatory BP measurements, daytime ambulatory SBP was significantly lower in the D+Ex group (134 mmHg; 95% confidence interval [CI], 131 to 137; p=0.011) than in the C group (139.5 mmHg; 95% CI, 130.9 to 137), and daytime ambulatory SBP was significantly decreased in the D+Ex group (?5.2 mmHg; 95% CI, ?8.3 to ?2.1; p=0.011) compared to the C group (0.4 mmHg, 95% CI, ?2.5 to 3.3). Conclusions: In conclusion, lifestyle modification emphasizing both diet and exercise was effective for lowering BP and should be favored over diet-only modifications.
AB - Background and Objectives: Supervised lifestyle interventions, including dietary and exercise programs, may be infeasible to implement in real-world settings. Therefore, this study aimed to evaluate the effectiveness of a home-based lifestyle modification intervention on blood pressure (BP) management. Methods: Eighty-five patients aged over 20 years and diagnosed with prehypertension or mild hypertension were randomly assigned to an advice-only comparison group (C group, n=28), a Dietary Approaches to Stop Hypertension (DASH) diet education group (D group, n=30), or a DASH and home-based exercise group (D+Ex group, n=27). The intervention lasted for 8 weeks. The primary outcome was the difference in office systolic blood pressure (SBP) before and after the study period (Trial registry at ClinicalTrials.gov, NCT01637909). Results: Seventy-two participants (87.8%) completed the trial. The degree of change in office SBP did not significantly differ among the intervention groups; however, the D+Ex group demonstrated a tendency toward decreased SBP. Upon analysis of 24-hour ambulatory BP measurements, daytime ambulatory SBP was significantly lower in the D+Ex group (134 mmHg; 95% confidence interval [CI], 131 to 137; p=0.011) than in the C group (139.5 mmHg; 95% CI, 130.9 to 137), and daytime ambulatory SBP was significantly decreased in the D+Ex group (?5.2 mmHg; 95% CI, ?8.3 to ?2.1; p=0.011) compared to the C group (0.4 mmHg, 95% CI, ?2.5 to 3.3). Conclusions: In conclusion, lifestyle modification emphasizing both diet and exercise was effective for lowering BP and should be favored over diet-only modifications.
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U2 - 10.4070/kcj.2017.0349
DO - 10.4070/kcj.2017.0349
M3 - Article
AN - SCOPUS:85049400104
VL - 48
SP - 637
EP - 651
JO - Korean Circulation Journal
JF - Korean Circulation Journal
SN - 1738-5520
IS - 7
ER -