The effects of multi-growth factors-containing cream on post-Thyroidectomy scars

A preliminary study

Sungsik Shin, Jung U. Shin, Youngin Lee, Woong Youn Chung, Kee Hyun Nam, Tae Gwang Kwon, JuHee Lee

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Growth factors play important roles in wound healing. However, the evidence for the effects of growth factors on post-Thyroidectomy scars is limited. Objective: We performed a prospective study to assess the preventive and therapeutic effect of a multi-growth factor (MGF)-containing cream on post-Thyroidectomy scars. Methods: Twenty-one patients with thyroidectomy scars applied MGF cream twice a day. We assessed the changes in erythema, pigmentation, skin elasticity, and skin hydration status using the erythema index, melanin index, cutometer, and corneometer, respectively. In addition, Vancouver scar scale (VSS) and patient satisfaction were assessed at 10 days after surgery (baseline), 2 weeks, 6 weeks, and 12 weeks after baseline. Results: The mean total VSS scores were significantly lower at 6 weeks (3.24±1.51 vs. 1.91±1.38) and 12 weeks (3.24±1.51 vs. 1.71±1.59) compared to the baseline. The degree of pigmentation was significantly lower at 12 weeks compared to the baseline, and the skin elasticity, and the skin hydration status were significantly higher at 12 weeks compared to the baseline. Over 85% of the patients were satisfied with the use of MGF cream without any adverse effect. Conclusion: MGF cream might have additive or supportive effect for scar formation after thyroidectomy.

Original languageEnglish
Pages (from-to)314-320
Number of pages7
JournalAnnals of Dermatology
Volume29
Issue number3
DOIs
Publication statusPublished - 2017 Jun 1

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Thyroidectomy
Cicatrix
Intercellular Signaling Peptides and Proteins
Elasticity
Erythema
Skin
Skin Pigmentation
Melanins
Pigmentation
Therapeutic Uses
Ambulatory Surgical Procedures
Patient Satisfaction
Wound Healing
Prospective Studies

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Shin, Sungsik ; Shin, Jung U. ; Lee, Youngin ; Chung, Woong Youn ; Nam, Kee Hyun ; Kwon, Tae Gwang ; Lee, JuHee. / The effects of multi-growth factors-containing cream on post-Thyroidectomy scars : A preliminary study. In: Annals of Dermatology. 2017 ; Vol. 29, No. 3. pp. 314-320.
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abstract = "Background: Growth factors play important roles in wound healing. However, the evidence for the effects of growth factors on post-Thyroidectomy scars is limited. Objective: We performed a prospective study to assess the preventive and therapeutic effect of a multi-growth factor (MGF)-containing cream on post-Thyroidectomy scars. Methods: Twenty-one patients with thyroidectomy scars applied MGF cream twice a day. We assessed the changes in erythema, pigmentation, skin elasticity, and skin hydration status using the erythema index, melanin index, cutometer, and corneometer, respectively. In addition, Vancouver scar scale (VSS) and patient satisfaction were assessed at 10 days after surgery (baseline), 2 weeks, 6 weeks, and 12 weeks after baseline. Results: The mean total VSS scores were significantly lower at 6 weeks (3.24±1.51 vs. 1.91±1.38) and 12 weeks (3.24±1.51 vs. 1.71±1.59) compared to the baseline. The degree of pigmentation was significantly lower at 12 weeks compared to the baseline, and the skin elasticity, and the skin hydration status were significantly higher at 12 weeks compared to the baseline. Over 85{\%} of the patients were satisfied with the use of MGF cream without any adverse effect. Conclusion: MGF cream might have additive or supportive effect for scar formation after thyroidectomy.",
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The effects of multi-growth factors-containing cream on post-Thyroidectomy scars : A preliminary study. / Shin, Sungsik; Shin, Jung U.; Lee, Youngin; Chung, Woong Youn; Nam, Kee Hyun; Kwon, Tae Gwang; Lee, JuHee.

In: Annals of Dermatology, Vol. 29, No. 3, 01.06.2017, p. 314-320.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The effects of multi-growth factors-containing cream on post-Thyroidectomy scars

T2 - A preliminary study

AU - Shin, Sungsik

AU - Shin, Jung U.

AU - Lee, Youngin

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AU - Nam, Kee Hyun

AU - Kwon, Tae Gwang

AU - Lee, JuHee

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N2 - Background: Growth factors play important roles in wound healing. However, the evidence for the effects of growth factors on post-Thyroidectomy scars is limited. Objective: We performed a prospective study to assess the preventive and therapeutic effect of a multi-growth factor (MGF)-containing cream on post-Thyroidectomy scars. Methods: Twenty-one patients with thyroidectomy scars applied MGF cream twice a day. We assessed the changes in erythema, pigmentation, skin elasticity, and skin hydration status using the erythema index, melanin index, cutometer, and corneometer, respectively. In addition, Vancouver scar scale (VSS) and patient satisfaction were assessed at 10 days after surgery (baseline), 2 weeks, 6 weeks, and 12 weeks after baseline. Results: The mean total VSS scores were significantly lower at 6 weeks (3.24±1.51 vs. 1.91±1.38) and 12 weeks (3.24±1.51 vs. 1.71±1.59) compared to the baseline. The degree of pigmentation was significantly lower at 12 weeks compared to the baseline, and the skin elasticity, and the skin hydration status were significantly higher at 12 weeks compared to the baseline. Over 85% of the patients were satisfied with the use of MGF cream without any adverse effect. Conclusion: MGF cream might have additive or supportive effect for scar formation after thyroidectomy.

AB - Background: Growth factors play important roles in wound healing. However, the evidence for the effects of growth factors on post-Thyroidectomy scars is limited. Objective: We performed a prospective study to assess the preventive and therapeutic effect of a multi-growth factor (MGF)-containing cream on post-Thyroidectomy scars. Methods: Twenty-one patients with thyroidectomy scars applied MGF cream twice a day. We assessed the changes in erythema, pigmentation, skin elasticity, and skin hydration status using the erythema index, melanin index, cutometer, and corneometer, respectively. In addition, Vancouver scar scale (VSS) and patient satisfaction were assessed at 10 days after surgery (baseline), 2 weeks, 6 weeks, and 12 weeks after baseline. Results: The mean total VSS scores were significantly lower at 6 weeks (3.24±1.51 vs. 1.91±1.38) and 12 weeks (3.24±1.51 vs. 1.71±1.59) compared to the baseline. The degree of pigmentation was significantly lower at 12 weeks compared to the baseline, and the skin elasticity, and the skin hydration status were significantly higher at 12 weeks compared to the baseline. Over 85% of the patients were satisfied with the use of MGF cream without any adverse effect. Conclusion: MGF cream might have additive or supportive effect for scar formation after thyroidectomy.

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