The effects of physical activity and body fat mass on colorectal polyp recurrence in patients with previous colorectal cancer

Jihye Park, Jae Hyun Kim, Hyun Jung Lee, Soo Jung Park, Sung Pil Hong, JaeHee Cheon, Won Ho Kim, Ji Soo Park, Justin Y. Jeon, Tae Il Kim

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We aimed to identify the effects of physical activity and body composition on colorectal polyp recurrence in patients with previous colorectal cancer. A total of 300 patients were selected randomly from the colorectal cancer survivor cohort of Severance Hospital (Seoul, Korea). Patients reported various recreational physical activities and received surveillance colonoscopy. Body composition was measured with a body composition analyzer. We compared patients who exercised for at least 1 hour/week (active) with those who exercised less frequently or not at all (sedentary). The active exercise group (n = 203) had a lower recurrence of advanced adenoma than the sedentary group (n = 97; 6.4% vs. 14.4%, P = 0.023). The prevalence of advanced adenoma recurrence decreased in an exercise dose-dependent manner (P trend  = 0.019). In multivariate logistic analysis, the independent factors associated with advanced polyp recurrence were body fat mass [OR, 7.601; 95% confidence interval (CI), 1.583–36.485; P = 0.011] and active exercise (OR, 0.340; 95% CI, 0.143–0.809; P = 0.015). In Cox proportional hazards models, body fat mass (HR, 5.315; 95% CI, 1.173–24.083; P = 0.030) and active exercise (HR, 0.367; 95% CI, 0.162–0.833; P = 0.017) were the independent factors associated with cumulative advanced adenoma recurrence. In conclusion, exercising for at least 1 hour/week and low body fat mass were found to be related to lower rates of colorectal polyp recurrence in the surveillance of colorectal cancer survivors.

Original languageEnglish
Pages (from-to)478-484
Number of pages7
JournalCancer Prevention Research
Volume10
Issue number8
DOIs
Publication statusPublished - 2017 Aug 1

Fingerprint

Polyps
Adipose Tissue
Colorectal Neoplasms
Exercise
Recurrence
Body Composition
Adenoma
Confidence Intervals
Survivors
Colonoscopy
Korea
Proportional Hazards Models
Multivariate Analysis

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Park, Jihye ; Kim, Jae Hyun ; Lee, Hyun Jung ; Park, Soo Jung ; Hong, Sung Pil ; Cheon, JaeHee ; Kim, Won Ho ; Park, Ji Soo ; Jeon, Justin Y. ; Kim, Tae Il. / The effects of physical activity and body fat mass on colorectal polyp recurrence in patients with previous colorectal cancer. In: Cancer Prevention Research. 2017 ; Vol. 10, No. 8. pp. 478-484.
@article{e710e038f5fb4b3eb33f0bb66cdc33bb,
title = "The effects of physical activity and body fat mass on colorectal polyp recurrence in patients with previous colorectal cancer",
abstract = "We aimed to identify the effects of physical activity and body composition on colorectal polyp recurrence in patients with previous colorectal cancer. A total of 300 patients were selected randomly from the colorectal cancer survivor cohort of Severance Hospital (Seoul, Korea). Patients reported various recreational physical activities and received surveillance colonoscopy. Body composition was measured with a body composition analyzer. We compared patients who exercised for at least 1 hour/week (active) with those who exercised less frequently or not at all (sedentary). The active exercise group (n = 203) had a lower recurrence of advanced adenoma than the sedentary group (n = 97; 6.4{\%} vs. 14.4{\%}, P = 0.023). The prevalence of advanced adenoma recurrence decreased in an exercise dose-dependent manner (P trend  = 0.019). In multivariate logistic analysis, the independent factors associated with advanced polyp recurrence were body fat mass [OR, 7.601; 95{\%} confidence interval (CI), 1.583–36.485; P = 0.011] and active exercise (OR, 0.340; 95{\%} CI, 0.143–0.809; P = 0.015). In Cox proportional hazards models, body fat mass (HR, 5.315; 95{\%} CI, 1.173–24.083; P = 0.030) and active exercise (HR, 0.367; 95{\%} CI, 0.162–0.833; P = 0.017) were the independent factors associated with cumulative advanced adenoma recurrence. In conclusion, exercising for at least 1 hour/week and low body fat mass were found to be related to lower rates of colorectal polyp recurrence in the surveillance of colorectal cancer survivors.",
author = "Jihye Park and Kim, {Jae Hyun} and Lee, {Hyun Jung} and Park, {Soo Jung} and Hong, {Sung Pil} and JaeHee Cheon and Kim, {Won Ho} and Park, {Ji Soo} and Jeon, {Justin Y.} and Kim, {Tae Il}",
year = "2017",
month = "8",
day = "1",
doi = "10.1158/1940-6207.CAPR-17-0065",
language = "English",
volume = "10",
pages = "478--484",
journal = "Cancer Prevention Research",
issn = "1940-6207",
publisher = "American Association for Cancer Research Inc.",
number = "8",

}

The effects of physical activity and body fat mass on colorectal polyp recurrence in patients with previous colorectal cancer. / Park, Jihye; Kim, Jae Hyun; Lee, Hyun Jung; Park, Soo Jung; Hong, Sung Pil; Cheon, JaeHee; Kim, Won Ho; Park, Ji Soo; Jeon, Justin Y.; Kim, Tae Il.

In: Cancer Prevention Research, Vol. 10, No. 8, 01.08.2017, p. 478-484.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The effects of physical activity and body fat mass on colorectal polyp recurrence in patients with previous colorectal cancer

AU - Park, Jihye

AU - Kim, Jae Hyun

AU - Lee, Hyun Jung

AU - Park, Soo Jung

AU - Hong, Sung Pil

AU - Cheon, JaeHee

AU - Kim, Won Ho

AU - Park, Ji Soo

AU - Jeon, Justin Y.

AU - Kim, Tae Il

PY - 2017/8/1

Y1 - 2017/8/1

N2 - We aimed to identify the effects of physical activity and body composition on colorectal polyp recurrence in patients with previous colorectal cancer. A total of 300 patients were selected randomly from the colorectal cancer survivor cohort of Severance Hospital (Seoul, Korea). Patients reported various recreational physical activities and received surveillance colonoscopy. Body composition was measured with a body composition analyzer. We compared patients who exercised for at least 1 hour/week (active) with those who exercised less frequently or not at all (sedentary). The active exercise group (n = 203) had a lower recurrence of advanced adenoma than the sedentary group (n = 97; 6.4% vs. 14.4%, P = 0.023). The prevalence of advanced adenoma recurrence decreased in an exercise dose-dependent manner (P trend  = 0.019). In multivariate logistic analysis, the independent factors associated with advanced polyp recurrence were body fat mass [OR, 7.601; 95% confidence interval (CI), 1.583–36.485; P = 0.011] and active exercise (OR, 0.340; 95% CI, 0.143–0.809; P = 0.015). In Cox proportional hazards models, body fat mass (HR, 5.315; 95% CI, 1.173–24.083; P = 0.030) and active exercise (HR, 0.367; 95% CI, 0.162–0.833; P = 0.017) were the independent factors associated with cumulative advanced adenoma recurrence. In conclusion, exercising for at least 1 hour/week and low body fat mass were found to be related to lower rates of colorectal polyp recurrence in the surveillance of colorectal cancer survivors.

AB - We aimed to identify the effects of physical activity and body composition on colorectal polyp recurrence in patients with previous colorectal cancer. A total of 300 patients were selected randomly from the colorectal cancer survivor cohort of Severance Hospital (Seoul, Korea). Patients reported various recreational physical activities and received surveillance colonoscopy. Body composition was measured with a body composition analyzer. We compared patients who exercised for at least 1 hour/week (active) with those who exercised less frequently or not at all (sedentary). The active exercise group (n = 203) had a lower recurrence of advanced adenoma than the sedentary group (n = 97; 6.4% vs. 14.4%, P = 0.023). The prevalence of advanced adenoma recurrence decreased in an exercise dose-dependent manner (P trend  = 0.019). In multivariate logistic analysis, the independent factors associated with advanced polyp recurrence were body fat mass [OR, 7.601; 95% confidence interval (CI), 1.583–36.485; P = 0.011] and active exercise (OR, 0.340; 95% CI, 0.143–0.809; P = 0.015). In Cox proportional hazards models, body fat mass (HR, 5.315; 95% CI, 1.173–24.083; P = 0.030) and active exercise (HR, 0.367; 95% CI, 0.162–0.833; P = 0.017) were the independent factors associated with cumulative advanced adenoma recurrence. In conclusion, exercising for at least 1 hour/week and low body fat mass were found to be related to lower rates of colorectal polyp recurrence in the surveillance of colorectal cancer survivors.

UR - http://www.scopus.com/inward/record.url?scp=85027035097&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85027035097&partnerID=8YFLogxK

U2 - 10.1158/1940-6207.CAPR-17-0065

DO - 10.1158/1940-6207.CAPR-17-0065

M3 - Article

VL - 10

SP - 478

EP - 484

JO - Cancer Prevention Research

JF - Cancer Prevention Research

SN - 1940-6207

IS - 8

ER -