Abstract
We evaluated the efficacy of dimercaptosuccinic acid (DMSA) scan and ultrasound (US) in comparison with voiding cystourethrography (VCUG) in predicting vesicoureteral reflux (VUR) in children below the age of 2 years. Medical records and radiologic studies of children (<2 years) suffering their first febrile urinary tract infection (UTI) between January 2001 and May 2007 were retrospectively reviewed. We evaluated the sensitivity, specificity, and positive and negative predictive values of US and DMSA scans in diagnosing VUR. Among 220 children with their first febrile UTI, VUR was detected in 67 (30.4%). The detection rate of VUR by US was 41.7% and 86% in the low (I, II) and high grade (III∼IV) groups, respectively. Detection rate of VUR by DMSA scan was 37.5% and 88.4% in the low and high grade groups, respectively. Combining US and DMSA scan, we found that the detection rate of high grade VUR was 95.3% and that of low grade was 62.5%. During follow up, most of the low grade VURs with normal DMSA and US scans resolved or were downgraded. Most high grade VURs could be detected by US and DMSA scan, but the prediction rate was not as high in low grade VURs. However, we can anticipate spontaneous improvement without complications in patients with either low or high grade reflux and negative findings on US and DMSA scan.
| Original language | English |
|---|---|
| Pages (from-to) | 2009-2013 |
| Number of pages | 5 |
| Journal | Pediatric Nephrology |
| Volume | 24 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2009 Jul 13 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health
- Nephrology
Cite this
}
The efficacy of ultrasound and dimercaptosuccinic acid scan in predicting vesicoureteral reflux in children below the age of 2 years with their first febrile urinary tract infection. / Lee, Hye Young; Hyun Soh, Byung; Hee Hong, Chang; Joon Kim, Myung; Won Han, Sang.
In: Pediatric Nephrology, Vol. 24, No. 10, 13.07.2009, p. 2009-2013.Research output: Contribution to journal › Article
TY - JOUR
T1 - The efficacy of ultrasound and dimercaptosuccinic acid scan in predicting vesicoureteral reflux in children below the age of 2 years with their first febrile urinary tract infection
AU - Lee, Hye Young
AU - Hyun Soh, Byung
AU - Hee Hong, Chang
AU - Joon Kim, Myung
AU - Won Han, Sang
PY - 2009/7/13
Y1 - 2009/7/13
N2 - We evaluated the efficacy of dimercaptosuccinic acid (DMSA) scan and ultrasound (US) in comparison with voiding cystourethrography (VCUG) in predicting vesicoureteral reflux (VUR) in children below the age of 2 years. Medical records and radiologic studies of children (<2 years) suffering their first febrile urinary tract infection (UTI) between January 2001 and May 2007 were retrospectively reviewed. We evaluated the sensitivity, specificity, and positive and negative predictive values of US and DMSA scans in diagnosing VUR. Among 220 children with their first febrile UTI, VUR was detected in 67 (30.4%). The detection rate of VUR by US was 41.7% and 86% in the low (I, II) and high grade (III∼IV) groups, respectively. Detection rate of VUR by DMSA scan was 37.5% and 88.4% in the low and high grade groups, respectively. Combining US and DMSA scan, we found that the detection rate of high grade VUR was 95.3% and that of low grade was 62.5%. During follow up, most of the low grade VURs with normal DMSA and US scans resolved or were downgraded. Most high grade VURs could be detected by US and DMSA scan, but the prediction rate was not as high in low grade VURs. However, we can anticipate spontaneous improvement without complications in patients with either low or high grade reflux and negative findings on US and DMSA scan.
AB - We evaluated the efficacy of dimercaptosuccinic acid (DMSA) scan and ultrasound (US) in comparison with voiding cystourethrography (VCUG) in predicting vesicoureteral reflux (VUR) in children below the age of 2 years. Medical records and radiologic studies of children (<2 years) suffering their first febrile urinary tract infection (UTI) between January 2001 and May 2007 were retrospectively reviewed. We evaluated the sensitivity, specificity, and positive and negative predictive values of US and DMSA scans in diagnosing VUR. Among 220 children with their first febrile UTI, VUR was detected in 67 (30.4%). The detection rate of VUR by US was 41.7% and 86% in the low (I, II) and high grade (III∼IV) groups, respectively. Detection rate of VUR by DMSA scan was 37.5% and 88.4% in the low and high grade groups, respectively. Combining US and DMSA scan, we found that the detection rate of high grade VUR was 95.3% and that of low grade was 62.5%. During follow up, most of the low grade VURs with normal DMSA and US scans resolved or were downgraded. Most high grade VURs could be detected by US and DMSA scan, but the prediction rate was not as high in low grade VURs. However, we can anticipate spontaneous improvement without complications in patients with either low or high grade reflux and negative findings on US and DMSA scan.
UR - http://www.scopus.com/inward/record.url?scp=70149098700&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70149098700&partnerID=8YFLogxK
U2 - 10.1007/s00467-009-1232-8
DO - 10.1007/s00467-009-1232-8
M3 - Article
C2 - 19593590
AN - SCOPUS:70149098700
VL - 24
SP - 2009
EP - 2013
JO - Pediatric Nephrology
JF - Pediatric Nephrology
SN - 0931-041X
IS - 10
ER -