The expression and cellular localization of phospholipase D isozymes in the developing mouse testis

Seungjoon Kim, Heechul Kim, Yongduk Lee, Won Hyun Jin, Ho Lee Young, Kyoung Shin Min, Sik Min Do, Taekyun Shin

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

To examine the involvement of phospholipase D (PLD) isozymes in postnatal testis development, the expression of PLD1 and PLD2 was examined in the mouse testis at postnatal weeks 1, 2, 4, and 8 using Western blot analysis and immunohistochemistry. The expression of both PLD1 and PLD2 increased gradually with development from postnatal week 1 to 8. Immunohistochemically, PLD immunoreactivity was detected in some germ cells in the testis and interstitial Leydig cells at postnatal week 1. PLD was mainly detected in the spermatocytes and residual bodies of spermatids in the testis after 8 weeks after birth. The intense immunostaining of PLD in Leydig cells remained unchanged by postnatal week 8. These findings suggest that PLD isozymes are involved in the spermatogenesis of the mouse testis.

Original languageEnglish
Pages (from-to)209-212
Number of pages4
JournalJournal of veterinary science
Volume8
Issue number3
DOIs
Publication statusPublished - 2007 Sep

All Science Journal Classification (ASJC) codes

  • veterinary(all)

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