The expression and cellular localization of phospholipase D1 in the rodent retina

Eun Jin Lee; Do Sik Min; Wha Sun Kang; Mun Yong Lee; Su Ja Oh; Myung Hoon Chun

doi:10.1016/S0006-8993(01)02516-1

The expression and cellular localization of phospholipase D1 in the rodent retina

Eun Jin Lee, Do Sik Min, Wha Sun Kang, Mun Yong Lee, Su Ja Oh, Myung Hoon Chun

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Phospholipase D (PLD) is one of the intracellular signal transduction enzymes and plays an important role in a variety of cellular functions. We investigated the expression and cellular localization of the PLD isozyme PLD1 in the rodent retina. Western blot analysis showed the presence of PLD1 at the protein level in the rat, mouse and guinea pig retinas. PLD1 immunoreactivity was localized in all Müller cells. Thus, PLD1 protein appears to be important in the functions of these cells in the rodent retina.

Original language	English
Pages (from-to)	240-244
Number of pages	5
Journal	Brain Research
Volume	905
Issue number	1-2
DOIs	https://doi.org/10.1016/S0006-8993(01)02516-1
Publication status	Published - 2001 Jun 29

Bibliographical note

Funding Information:
This work was supported by a KOSEF (2000-1-20700-008-3) grant from the Korea Science and Engineering Foundation in 2000. We are grateful to H.-D. Rho and B.-W. Hong for their technical assistance.

All Science Journal Classification (ASJC) codes

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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title = "The expression and cellular localization of phospholipase D1 in the rodent retina",

abstract = "Phospholipase D (PLD) is one of the intracellular signal transduction enzymes and plays an important role in a variety of cellular functions. We investigated the expression and cellular localization of the PLD isozyme PLD1 in the rodent retina. Western blot analysis showed the presence of PLD1 at the protein level in the rat, mouse and guinea pig retinas. PLD1 immunoreactivity was localized in all M{\"u}ller cells. Thus, PLD1 protein appears to be important in the functions of these cells in the rodent retina.",

author = "Lee, {Eun Jin} and Min, {Do Sik} and Kang, {Wha Sun} and Lee, {Mun Yong} and Oh, {Su Ja} and Chun, {Myung Hoon}",

note = "Funding Information: This work was supported by a KOSEF (2000-1-20700-008-3) grant from the Korea Science and Engineering Foundation in 2000. We are grateful to H.-D. Rho and B.-W. Hong for their technical assistance.",

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AU - Lee, Eun Jin

AU - Min, Do Sik

AU - Kang, Wha Sun

AU - Lee, Mun Yong

AU - Oh, Su Ja

AU - Chun, Myung Hoon

N1 - Funding Information: This work was supported by a KOSEF (2000-1-20700-008-3) grant from the Korea Science and Engineering Foundation in 2000. We are grateful to H.-D. Rho and B.-W. Hong for their technical assistance.

PY - 2001/6/29

Y1 - 2001/6/29

N2 - Phospholipase D (PLD) is one of the intracellular signal transduction enzymes and plays an important role in a variety of cellular functions. We investigated the expression and cellular localization of the PLD isozyme PLD1 in the rodent retina. Western blot analysis showed the presence of PLD1 at the protein level in the rat, mouse and guinea pig retinas. PLD1 immunoreactivity was localized in all Müller cells. Thus, PLD1 protein appears to be important in the functions of these cells in the rodent retina.

AB - Phospholipase D (PLD) is one of the intracellular signal transduction enzymes and plays an important role in a variety of cellular functions. We investigated the expression and cellular localization of the PLD isozyme PLD1 in the rodent retina. Western blot analysis showed the presence of PLD1 at the protein level in the rat, mouse and guinea pig retinas. PLD1 immunoreactivity was localized in all Müller cells. Thus, PLD1 protein appears to be important in the functions of these cells in the rodent retina.

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The expression and cellular localization of phospholipase D1 in the rodent retina

Abstract

Bibliographical note

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