The first Korean case of nontuberculous mycobacterial lung disease caused by Mycobacterium abscessus subspecies bolletii in a patient with bronchiectasis

Byeong Ho Jeong, Su Young Kim, Kyeongman Jeon, Hee Jae Huh, Chang Seok Ki, Nam Yong Lee, Sung Jae Shin, Won Jung Koh

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We report the first Korean case of lung diseases caused by Mycobacterium abscessus subsp. bolletii in a previously healthy male, except for a previous history of pulmonary tuberculosis and bronchiectasis. All serial isolates are identified as M. abscessus subsp. bolletii by multi-locus sequence analysis based on the hsp65, rpoB, and 16S rRNA fragments. At the genetic level, the isolate has the erm(41) gene with a T28 sequevar, associated with clarithromycin resistance, and no rrl mutation. The isolate is resistant to clarithromycin. Although the symptoms and radiographic findings have improved after combination of antibiotics, the follow-up sputum cultures are persistently positive.

Original languageEnglish
Pages (from-to)30-33
Number of pages4
JournalTuberculosis and Respiratory Diseases
Volume76
Issue number1
DOIs
Publication statusPublished - 2014 Jan 1

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Bronchiectasis
Clarithromycin
Mycobacterium
Lung Diseases
Sputum
Pulmonary Tuberculosis
Sequence Analysis
Anti-Bacterial Agents
Mutation
Genes

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

Cite this

Jeong, Byeong Ho ; Kim, Su Young ; Jeon, Kyeongman ; Huh, Hee Jae ; Ki, Chang Seok ; Lee, Nam Yong ; Shin, Sung Jae ; Koh, Won Jung. / The first Korean case of nontuberculous mycobacterial lung disease caused by Mycobacterium abscessus subspecies bolletii in a patient with bronchiectasis. In: Tuberculosis and Respiratory Diseases. 2014 ; Vol. 76, No. 1. pp. 30-33.
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The first Korean case of nontuberculous mycobacterial lung disease caused by Mycobacterium abscessus subspecies bolletii in a patient with bronchiectasis. / Jeong, Byeong Ho; Kim, Su Young; Jeon, Kyeongman; Huh, Hee Jae; Ki, Chang Seok; Lee, Nam Yong; Shin, Sung Jae; Koh, Won Jung.

In: Tuberculosis and Respiratory Diseases, Vol. 76, No. 1, 01.01.2014, p. 30-33.

Research output: Contribution to journalArticle

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AU - Jeong, Byeong Ho

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