The first Korean case of nontuberculous mycobacterial lung disease caused by Mycobacterium abscessus subspecies bolletii in a patient with bronchiectasis

Byeong Ho Jeong, Su Young Kim, Kyeongman Jeon, Hee Jae Huh, Chang Seok Ki, Nam Yong Lee, Sung Jae Shin, Won Jung Koh

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We report the first Korean case of lung diseases caused by Mycobacterium abscessus subsp. bolletii in a previously healthy male, except for a previous history of pulmonary tuberculosis and bronchiectasis. All serial isolates are identified as M. abscessus subsp. bolletii by multi-locus sequence analysis based on the hsp65, rpoB, and 16S rRNA fragments. At the genetic level, the isolate has the erm(41) gene with a T28 sequevar, associated with clarithromycin resistance, and no rrl mutation. The isolate is resistant to clarithromycin. Although the symptoms and radiographic findings have improved after combination of antibiotics, the follow-up sputum cultures are persistently positive.

Original languageEnglish
Pages (from-to)30-33
Number of pages4
JournalTuberculosis and Respiratory Diseases
Issue number1
Publication statusPublished - 2014 Jan 1


All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

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