The first neural probe integrated with light source (blue laser diode) for optical stimulation and electrical recording

Hyungdal Park, Hyun Joon Shin, Il Joo Cho, Eui Sung Yoon, Jun Kyo Francis Suh, Maesoon Im, Euisik Yoon, Yong-Jun Kim, Jinseok Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Citations (Scopus)

Abstract

In this paper, we report a neural probe which can selectively stimulate target neurons optically through Si wet etched mirror surface and record extracellular neural signals in iridium oxide tetrodes. Consequently, the proposed approach provides to improve directional problem and achieve at least 150/m gap distance between stimulation and recording sites by wet etched mirror surface in V-groove. Also, we developed light source, blue laser diode (OSRAM Blue Laser Diode-PL 450), integration through simple jig for one-touch butt-coupling. Furthermore, optical power and impedance of iridium oxide tetrodes were measured as 200W on 5mW from LD and 206.5k at 1kHz and we demonstrated insertion test of probe in 0.5% agarose-gel successfully. We have successfully transmitted a light of 450nm to optical fiber through the integrated LD using by butt-coupling method.

Original languageEnglish
Title of host publication33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Pages2961-2964
Number of pages4
DOIs
Publication statusPublished - 2011 Dec 26
Event33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States
Duration: 2011 Aug 302011 Sep 3

Other

Other33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
CountryUnited States
CityBoston, MA
Period11/8/3011/9/3

Fingerprint

Tetrodes
Semiconductor Lasers
Iridium
Electric Stimulation
Light sources
Semiconductor lasers
Mirrors
Optical Fibers
Light
Jigs
Oxides
Touch
Electric Impedance
Sepharose
Neurons
Optical fibers
Gels
iridium oxide

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Park, H., Shin, H. J., Cho, I. J., Yoon, E. S., Suh, J. K. F., Im, M., ... Kim, J. (2011). The first neural probe integrated with light source (blue laser diode) for optical stimulation and electrical recording. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 (pp. 2961-2964). [6090813] https://doi.org/10.1109/IEMBS.2011.6090813
Park, Hyungdal ; Shin, Hyun Joon ; Cho, Il Joo ; Yoon, Eui Sung ; Suh, Jun Kyo Francis ; Im, Maesoon ; Yoon, Euisik ; Kim, Yong-Jun ; Kim, Jinseok. / The first neural probe integrated with light source (blue laser diode) for optical stimulation and electrical recording. 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. 2011. pp. 2961-2964
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title = "The first neural probe integrated with light source (blue laser diode) for optical stimulation and electrical recording",
abstract = "In this paper, we report a neural probe which can selectively stimulate target neurons optically through Si wet etched mirror surface and record extracellular neural signals in iridium oxide tetrodes. Consequently, the proposed approach provides to improve directional problem and achieve at least 150/m gap distance between stimulation and recording sites by wet etched mirror surface in V-groove. Also, we developed light source, blue laser diode (OSRAM Blue Laser Diode-PL 450), integration through simple jig for one-touch butt-coupling. Furthermore, optical power and impedance of iridium oxide tetrodes were measured as 200W on 5mW from LD and 206.5k at 1kHz and we demonstrated insertion test of probe in 0.5{\%} agarose-gel successfully. We have successfully transmitted a light of 450nm to optical fiber through the integrated LD using by butt-coupling method.",
author = "Hyungdal Park and Shin, {Hyun Joon} and Cho, {Il Joo} and Yoon, {Eui Sung} and Suh, {Jun Kyo Francis} and Maesoon Im and Euisik Yoon and Yong-Jun Kim and Jinseok Kim",
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Park, H, Shin, HJ, Cho, IJ, Yoon, ES, Suh, JKF, Im, M, Yoon, E, Kim, Y-J & Kim, J 2011, The first neural probe integrated with light source (blue laser diode) for optical stimulation and electrical recording. in 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011., 6090813, pp. 2961-2964, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011, Boston, MA, United States, 11/8/30. https://doi.org/10.1109/IEMBS.2011.6090813

The first neural probe integrated with light source (blue laser diode) for optical stimulation and electrical recording. / Park, Hyungdal; Shin, Hyun Joon; Cho, Il Joo; Yoon, Eui Sung; Suh, Jun Kyo Francis; Im, Maesoon; Yoon, Euisik; Kim, Yong-Jun; Kim, Jinseok.

33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. 2011. p. 2961-2964 6090813.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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AU - Park, Hyungdal

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AU - Suh, Jun Kyo Francis

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AU - Kim, Jinseok

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AB - In this paper, we report a neural probe which can selectively stimulate target neurons optically through Si wet etched mirror surface and record extracellular neural signals in iridium oxide tetrodes. Consequently, the proposed approach provides to improve directional problem and achieve at least 150/m gap distance between stimulation and recording sites by wet etched mirror surface in V-groove. Also, we developed light source, blue laser diode (OSRAM Blue Laser Diode-PL 450), integration through simple jig for one-touch butt-coupling. Furthermore, optical power and impedance of iridium oxide tetrodes were measured as 200W on 5mW from LD and 206.5k at 1kHz and we demonstrated insertion test of probe in 0.5% agarose-gel successfully. We have successfully transmitted a light of 450nm to optical fiber through the integrated LD using by butt-coupling method.

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Park H, Shin HJ, Cho IJ, Yoon ES, Suh JKF, Im M et al. The first neural probe integrated with light source (blue laser diode) for optical stimulation and electrical recording. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. 2011. p. 2961-2964. 6090813 https://doi.org/10.1109/IEMBS.2011.6090813