The Functional Relationships between Hiatal Hernia and Reflux Esophagitis

HyoJin Park, Jong Doo Lee, Jim Keun Jung, Byung Soo Moon, Peter J. Collins, In Suh Park

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The purpose of this research was to investigate functional studies by which the hiatal hernia (HH) may be relevant to a reflux esophagitis (RE). Group I consisted of healthy controls who were endoscopically normal (n=21). Group II consisted of patients with hiatal hernia but no reflux esophagitis (n=8). Group III had patients with hiatal hernia with reflux esophagitis (n=9). Group TV had patients with reflux esophagitis but no hiatal hernia (n=16), Esophageal manometry, ambulatory 24 hour intraesophageal pH monitoring, acid clearance test, and gastric emptying scan were performed in each of the patients. The contraction amplitude at 3cm above the lower esophageal sphincter did not differ significantly among the four groups, but the mean lower esophageal sphincter pressure was significantly decreased in group II. The DeMeester score in ambulatory 24 hour intraesophageal pH monitoring was significantly higher in group III compared with the controls. No significant difference among the groups was found with respect to acid clearance. Total and proximal gastric emptying times (T 1/2 ) were significantly delayed in group III. We found that hiatal hernia combined with delayed gastric emptying may bear a relationship to the multifactorial origins of reflux esophagitis, and we suggest a rationale for using prokinetic agents as the therapeutic regimen in patients with HH complicated by RE.

Original languageEnglish
Pages (from-to)278-283
Number of pages6
JournalYonsei medical journal
Volume37
Issue number4
DOIs
Publication statusPublished - 1996 Jan 1

Fingerprint

Peptic Esophagitis
Hiatal Hernia
Gastric Emptying
Lower Esophageal Sphincter
Acids
Manometry
Pressure
Research

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Park, H., Lee, J. D., Jung, J. K., Moon, B. S., Collins, P. J., & Park, I. S. (1996). The Functional Relationships between Hiatal Hernia and Reflux Esophagitis. Yonsei medical journal, 37(4), 278-283. https://doi.org/10.3349/ymj.1996.37.4.278
Park, HyoJin ; Lee, Jong Doo ; Jung, Jim Keun ; Moon, Byung Soo ; Collins, Peter J. ; Park, In Suh. / The Functional Relationships between Hiatal Hernia and Reflux Esophagitis. In: Yonsei medical journal. 1996 ; Vol. 37, No. 4. pp. 278-283.
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The Functional Relationships between Hiatal Hernia and Reflux Esophagitis. / Park, HyoJin; Lee, Jong Doo; Jung, Jim Keun; Moon, Byung Soo; Collins, Peter J.; Park, In Suh.

In: Yonsei medical journal, Vol. 37, No. 4, 01.01.1996, p. 278-283.

Research output: Contribution to journalArticle

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