The impact of dialysis modality on arterial stiffness in patients with end-stage renal disease

Jae Hyun Chang, Se Jung Yoon, SeungHyeok Han, Sug Kyun Shin, Dong Woon Jeon, Joo Young Yang, Ea Wha Kang

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: Arterial stiffness determined by brachialankle pulse wave velocity (baPWV) has been established as a powerful predictor of cardiovascular mortality in hemodialysis (HD) patients. There are, however, few studies regarding the comparative impact of different renal replacement therapies (RRTs) on PWV. Therefore, we conducted a cross-sectional study to compare arterial wall properties and cardiac function between patients treated with continuous ambulatory peritoneal dialysis (CAPD) and those with HD who were matched for age, dialysis duration, and blood pressure. Methods: baPWV and transthoracic echocardiography (TTE) were performed in HD patients (n = 23) after 1 h of midweek dialysis session and CAPD patients (n = 26) with empty abdomen after drainage of dialysate. The baseline data were retrospectively reviewed. Results: baPWV was significantly higher in HD patients than in CAPD patients (18.1 ± 2.8 vs. 16.1 ± 2.7 ms, p = 0.015). TTE revealed significantly increased EE′, left atrial volume index (LAVI), and inferior vena cava (IVC) diameter index in HD patients compared with CAPD patients (p < 0.05). In a multivariate regression analysis adjusted for dialysis modality, age, systolic BP, residual glomerular filtration rate, diabetes, and echocardiographic parameters, HD was independently associated with increased baPWV. Conclusion: This study showed that HD patients had significantly increased arterial stiffness and severe diastolic dysfunction compared with CAPD patients.

Original languageEnglish
Pages (from-to)947-953
Number of pages7
JournalRenal Failure
Volume32
Issue number8
DOIs
Publication statusPublished - 2010 Sep 1

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Vascular Stiffness
Chronic Kidney Failure
Dialysis
Renal Dialysis
Continuous Ambulatory Peritoneal Dialysis
Pulse Wave Analysis
Echocardiography
Renal Replacement Therapy
Dialysis Solutions
Inferior Vena Cava
Glomerular Filtration Rate
Abdomen
Drainage
Multivariate Analysis
Cross-Sectional Studies
Regression Analysis
Blood Pressure

All Science Journal Classification (ASJC) codes

  • Critical Care and Intensive Care Medicine
  • Nephrology

Cite this

Chang, J. H., Yoon, S. J., Han, S., Shin, S. K., Jeon, D. W., Yang, J. Y., & Kang, E. W. (2010). The impact of dialysis modality on arterial stiffness in patients with end-stage renal disease. Renal Failure, 32(8), 947-953. https://doi.org/10.3109/0886022X.2010.502607
Chang, Jae Hyun ; Yoon, Se Jung ; Han, SeungHyeok ; Shin, Sug Kyun ; Jeon, Dong Woon ; Yang, Joo Young ; Kang, Ea Wha. / The impact of dialysis modality on arterial stiffness in patients with end-stage renal disease. In: Renal Failure. 2010 ; Vol. 32, No. 8. pp. 947-953.
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The impact of dialysis modality on arterial stiffness in patients with end-stage renal disease. / Chang, Jae Hyun; Yoon, Se Jung; Han, SeungHyeok; Shin, Sug Kyun; Jeon, Dong Woon; Yang, Joo Young; Kang, Ea Wha.

In: Renal Failure, Vol. 32, No. 8, 01.09.2010, p. 947-953.

Research output: Contribution to journalArticle

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T1 - The impact of dialysis modality on arterial stiffness in patients with end-stage renal disease

AU - Chang, Jae Hyun

AU - Yoon, Se Jung

AU - Han, SeungHyeok

AU - Shin, Sug Kyun

AU - Jeon, Dong Woon

AU - Yang, Joo Young

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