The incidence and clinical impact of stent strut fractures developed after drug-eluting stent implantation

Wook Sung Chung, Chul Soo Park, Ki Bae Seung, Pum Joon Kim, Jong Min Lee, Bon Kwon Koo, Yangsoo Jang, Joo Young Yang, Junghan Yoon, Doo Il Kim, Young Won Yoon, Jong Seon Park, Yoon Haeng Cho, Seung Jung Park

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Background: Cases of stent strut fractures (SSFs) after DES implantation have been reported, but the clinical significance is uncertain. Then we sought to define the incidence and clinical implications of SSFs developed after drug-eluting stent (DES) implantation. Methods: We gathered SSF cases from 13 centers in Korea retrospectively. SSF was defined as angiographically visible interrupted connection of stent struts or fewer visible stent struts at the suspected site than normally looking stented area on intravascular ultrasound (IVUS). Furthermore, we classified the SSFs cases into three patterns (disruption, avulsion, and displacement) according to the interruption site and absence or presence of displacement. Results: Thirty-seven SSFs (2 disruption, 7 avulsion, 28 displacement) were detected in 35 lesions in 35 patients. All fractured stents were sirolimus-eluting stents (SESs). The incidence of SSFs was 0.84% and the proportion of restenosis related with SSF was 6.3% after SES implantation driven from the data of 8 centers. The average length of stent used was 49 mm, overlapping stenting was performed in 19 lesions (54%), and the average maximal angulation in the initial coronary angiography was 67°. Twenty-four fractures (65%) were associated with focal in stent restenosis and 11 fractures (30%) with target lesion revascularization. No acute coronary syndrome developed. Conclusions: SSF after DES implantation might be a considerable complication after DES implantation especially after SES implantation.

Original languageEnglish
Pages (from-to)325-331
Number of pages7
JournalInternational Journal of Cardiology
Volume125
Issue number3
DOIs
Publication statusPublished - 2008 Apr 25

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Drug-Eluting Stents
Stents
Incidence
Sirolimus
Acute Coronary Syndrome
Korea

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Chung, Wook Sung ; Park, Chul Soo ; Seung, Ki Bae ; Kim, Pum Joon ; Lee, Jong Min ; Koo, Bon Kwon ; Jang, Yangsoo ; Yang, Joo Young ; Yoon, Junghan ; Kim, Doo Il ; Yoon, Young Won ; Park, Jong Seon ; Cho, Yoon Haeng ; Park, Seung Jung. / The incidence and clinical impact of stent strut fractures developed after drug-eluting stent implantation. In: International Journal of Cardiology. 2008 ; Vol. 125, No. 3. pp. 325-331.
@article{8328e397a3014eadb8df74fadfa10143,
title = "The incidence and clinical impact of stent strut fractures developed after drug-eluting stent implantation",
abstract = "Background: Cases of stent strut fractures (SSFs) after DES implantation have been reported, but the clinical significance is uncertain. Then we sought to define the incidence and clinical implications of SSFs developed after drug-eluting stent (DES) implantation. Methods: We gathered SSF cases from 13 centers in Korea retrospectively. SSF was defined as angiographically visible interrupted connection of stent struts or fewer visible stent struts at the suspected site than normally looking stented area on intravascular ultrasound (IVUS). Furthermore, we classified the SSFs cases into three patterns (disruption, avulsion, and displacement) according to the interruption site and absence or presence of displacement. Results: Thirty-seven SSFs (2 disruption, 7 avulsion, 28 displacement) were detected in 35 lesions in 35 patients. All fractured stents were sirolimus-eluting stents (SESs). The incidence of SSFs was 0.84{\%} and the proportion of restenosis related with SSF was 6.3{\%} after SES implantation driven from the data of 8 centers. The average length of stent used was 49 mm, overlapping stenting was performed in 19 lesions (54{\%}), and the average maximal angulation in the initial coronary angiography was 67°. Twenty-four fractures (65{\%}) were associated with focal in stent restenosis and 11 fractures (30{\%}) with target lesion revascularization. No acute coronary syndrome developed. Conclusions: SSF after DES implantation might be a considerable complication after DES implantation especially after SES implantation.",
author = "Chung, {Wook Sung} and Park, {Chul Soo} and Seung, {Ki Bae} and Kim, {Pum Joon} and Lee, {Jong Min} and Koo, {Bon Kwon} and Yangsoo Jang and Yang, {Joo Young} and Junghan Yoon and Kim, {Doo Il} and Yoon, {Young Won} and Park, {Jong Seon} and Cho, {Yoon Haeng} and Park, {Seung Jung}",
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Chung, WS, Park, CS, Seung, KB, Kim, PJ, Lee, JM, Koo, BK, Jang, Y, Yang, JY, Yoon, J, Kim, DI, Yoon, YW, Park, JS, Cho, YH & Park, SJ 2008, 'The incidence and clinical impact of stent strut fractures developed after drug-eluting stent implantation', International Journal of Cardiology, vol. 125, no. 3, pp. 325-331. https://doi.org/10.1016/j.ijcard.2007.02.033

The incidence and clinical impact of stent strut fractures developed after drug-eluting stent implantation. / Chung, Wook Sung; Park, Chul Soo; Seung, Ki Bae; Kim, Pum Joon; Lee, Jong Min; Koo, Bon Kwon; Jang, Yangsoo; Yang, Joo Young; Yoon, Junghan; Kim, Doo Il; Yoon, Young Won; Park, Jong Seon; Cho, Yoon Haeng; Park, Seung Jung.

In: International Journal of Cardiology, Vol. 125, No. 3, 25.04.2008, p. 325-331.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The incidence and clinical impact of stent strut fractures developed after drug-eluting stent implantation

AU - Chung, Wook Sung

AU - Park, Chul Soo

AU - Seung, Ki Bae

AU - Kim, Pum Joon

AU - Lee, Jong Min

AU - Koo, Bon Kwon

AU - Jang, Yangsoo

AU - Yang, Joo Young

AU - Yoon, Junghan

AU - Kim, Doo Il

AU - Yoon, Young Won

AU - Park, Jong Seon

AU - Cho, Yoon Haeng

AU - Park, Seung Jung

PY - 2008/4/25

Y1 - 2008/4/25

N2 - Background: Cases of stent strut fractures (SSFs) after DES implantation have been reported, but the clinical significance is uncertain. Then we sought to define the incidence and clinical implications of SSFs developed after drug-eluting stent (DES) implantation. Methods: We gathered SSF cases from 13 centers in Korea retrospectively. SSF was defined as angiographically visible interrupted connection of stent struts or fewer visible stent struts at the suspected site than normally looking stented area on intravascular ultrasound (IVUS). Furthermore, we classified the SSFs cases into three patterns (disruption, avulsion, and displacement) according to the interruption site and absence or presence of displacement. Results: Thirty-seven SSFs (2 disruption, 7 avulsion, 28 displacement) were detected in 35 lesions in 35 patients. All fractured stents were sirolimus-eluting stents (SESs). The incidence of SSFs was 0.84% and the proportion of restenosis related with SSF was 6.3% after SES implantation driven from the data of 8 centers. The average length of stent used was 49 mm, overlapping stenting was performed in 19 lesions (54%), and the average maximal angulation in the initial coronary angiography was 67°. Twenty-four fractures (65%) were associated with focal in stent restenosis and 11 fractures (30%) with target lesion revascularization. No acute coronary syndrome developed. Conclusions: SSF after DES implantation might be a considerable complication after DES implantation especially after SES implantation.

AB - Background: Cases of stent strut fractures (SSFs) after DES implantation have been reported, but the clinical significance is uncertain. Then we sought to define the incidence and clinical implications of SSFs developed after drug-eluting stent (DES) implantation. Methods: We gathered SSF cases from 13 centers in Korea retrospectively. SSF was defined as angiographically visible interrupted connection of stent struts or fewer visible stent struts at the suspected site than normally looking stented area on intravascular ultrasound (IVUS). Furthermore, we classified the SSFs cases into three patterns (disruption, avulsion, and displacement) according to the interruption site and absence or presence of displacement. Results: Thirty-seven SSFs (2 disruption, 7 avulsion, 28 displacement) were detected in 35 lesions in 35 patients. All fractured stents were sirolimus-eluting stents (SESs). The incidence of SSFs was 0.84% and the proportion of restenosis related with SSF was 6.3% after SES implantation driven from the data of 8 centers. The average length of stent used was 49 mm, overlapping stenting was performed in 19 lesions (54%), and the average maximal angulation in the initial coronary angiography was 67°. Twenty-four fractures (65%) were associated with focal in stent restenosis and 11 fractures (30%) with target lesion revascularization. No acute coronary syndrome developed. Conclusions: SSF after DES implantation might be a considerable complication after DES implantation especially after SES implantation.

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