Purpose: Patients with intestinal Behçet’s disease who underwent intestinal resective surgery often require reoperation. However, there have been no studies on the risk factors and outcomes of early reoperation in these patients. Methods: We retrospectively evaluated 41 patients with intestinal Behçet’s disease who received repeated intestinal resective surgeries between 2006 and 2016. We analyzed two different patient groups—those who required early reoperation within 6 months and those who underwent reoperation >6 months after the initial surgery—and determined the risk factors for early reoperation. Results: Eleven patients (26.8%) underwent reoperation within 6 months and 30 patients (73.2%) after 6 months. Emergency surgery at the initial operation and higher initial perioperative erythrocyte sedimentation rate and C-reactive protein levels were significantly associated with early reoperation in the univariate analysis. After the multivariate analysis, initial emergency operation (P = 0.020; hazard ratio [HR], 42.625; 95% confidence interval [CI], 1.817–1000.088) and high erythrocyte sedimentation rate (P = 0.039; HR, 1.049; 95% CI, 1.002–1.097) were determined to be the independent factors for early reoperation. Conclusions: Emergency surgery and high perioperative erythrocyte sedimentation rate levels were the prognostic factors for early reoperation (within 6 months) in patients with intestinal Behçet’s disease after initial bowel resective surgery.
Bibliographical noteFunding Information:
This research was supported by two grants (A120176 and HI13C1345) from the Korean Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), which is funded by the Ministry of Health and Welfare, Republic of Korea; two grants (NRF-2013R1A2A2A01067123 and NRF-2014R1A1A1008096) from the Basic Science Research Program through the National Research Foundation of Korea, which is funded by the Ministry of Science, ICT and Future Planning; a faculty research grant (2012-31-0477) from the Department of Internal Medicine, Yonsei University, College of Medicine.
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