The prognostic implication of metabolic syndrome in patients with heart failure

Hyun Ju Yoon, Youngkeun Ahn, Kye Hun Kim, Jong Chun Park, Dong Ju Choi, Seongwoo Han, Eun Seok Jeon, Myung Chan Cho, Jae Joong Kim, Byung Su Yoo, Mi Seung Shin, In Whan Seong, Seok Min Kang, Yung Jo Kim, Hyung Seop Kim, Shung Chull Chae, Byung Hee Oh, Myung Mook Lee, Kyu Hyung Ryu

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Abstract

Background and Objectives: Metabolic syndrome (MetS) increases the risk of heart failure (HF). The purpose of this study was to identify the prevalence of MetS in patients with HF and determine the syndrome's association with HF in clinical and laboratory parameters. Subjects and Methods: A total of 3200 HF patients (67.6±14.5 years) enrolled in a nationwide prospective Korea HF Registry between Jan. 2005 and Oct. 2009. Patients were divided into two groups according to the presence or absence of MetS at admission: group I (presence, n=1141) and group II (absence, n=2059). Results: The prevalence of MetS was 35.7% across all subjects and was higher in females (56.0%). The levels of white blood cells, platelets, creatinine, glucose, and cholesterol were significantly higher in group I than in group II. Left ventricular dimension and volume was smaller and ejection fraction was higher in group I than in group II. An ischemic cause of HF was more frequent in group I. The rates of valvular and idiopathic cause were lower in group I than in group II. The rate of mortality was lower in group I than in group II (4.9% vs. 8.3%, p<0.001). Conclusion: Despite the increased cardiovascular risks in MetS, MetS was found to be associated with decreased mortality in HF.

Original languageEnglish
Pages (from-to)87-92
Number of pages6
JournalKorean Circulation Journal
Volume43
Issue number2
DOIs
Publication statusPublished - 2013 Feb 1

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All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Yoon, H. J., Ahn, Y., Kim, K. H., Park, J. C., Choi, D. J., Han, S., Jeon, E. S., Cho, M. C., Kim, J. J., Yoo, B. S., Shin, M. S., Seong, I. W., Kang, S. M., Kim, Y. J., Kim, H. S., Chae, S. C., Oh, B. H., Lee, M. M., & Ryu, K. H. (2013). The prognostic implication of metabolic syndrome in patients with heart failure. Korean Circulation Journal, 43(2), 87-92. https://doi.org/10.4070/kcj.2013.43.2.87